A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr
about
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testescDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteinsCDC42 and FGD1 cause distinct signaling and transforming activities.Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targetingOligomerization of DH domain is essential for Dbl-induced transformationA novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathwaysLocalization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysisTyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOSRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationThe Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinGenetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeastCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity.The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domainsApoptotic cell recognition receptors and scavenger receptors.Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24.Tyrosine phosphorylation of Dbl regulates GTPase signalingDependence of Dbl and Dbs transformation on MEK and NF-kappaB activation.Autoinhibition mechanism of proto-Dbl.Suppressors of the unc-73 gene of Caenorhabditis elegans.Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin.Kaposi's sarcoma-associated herpesvirus microRNAs repress breakpoint cluster region protein expression, enhance Rac1 activity, and increase in vitro angiogenesis.Dbl oncogene expression in MCF-10 A epithelial cells disrupts mammary acinar architecture, induces EMT and angiogenic factor secretionRegulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.Functional interaction between p21rap1A and components of the budding pathway in Saccharomyces cerevisiae.Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells.Insights into the biological functions of Dock family guanine nucleotide exchange factors.Lip, a human gene detected by transfection of DNA from a human liposarcoma encodes a protein with homology to regulators of small g proteins.Growth arrest-inducing genes are activated in Dbl-transformed mouse fibroblasts.DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila.A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila.A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins.Measurement of ploidy and cell proliferation in the rodent liver.Bcr and Raf form a complex in vivo via 14-3-3 proteins.RAS residues that are distant from the GDP binding site play a critical role in dissociation factor-stimulated release of GDP.A novel suppressor of ras1 in fission yeast, byr4, is a dosage-dependent inhibitor of cytokinesis.Regional localization and developmental expression of the BCR gene in rodent brain.
P2860
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P2860
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr
description
1991 nî lūn-bûn
@nan
1991 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@ast
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@en
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@nl
type
label
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@ast
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@en
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@nl
prefLabel
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@ast
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@en
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@nl
P2093
P1433
P1476
A region of proto-dbl essentia ...... n breakpoint cluster gene, bcr
@en
P2093
G Graziani
S A Aaronson
S R Tronick
P407
P50
P577
1991-04-01T00:00:00Z