Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone
about
Paget's disease of bone: an osteoimmunological disorder?Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone.Osteosarcoma in Paget's disease of bone.The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.The regulation of proteasome degradation by multi-ubiquitin chain binding proteins.Sequestosome 1/p62--more than just a scaffold.A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironmentOsteoclast inhibitory peptide-1 (OIP-1) inhibits measles virus nucleocapsid protein stimulated osteoclast formation/activity.Sequestosome 1/p62: across diseases.The role of ubiquitin-binding domains in human pathophysiology.Biology and Treatment of Paget's Disease of Bone.Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation.p62/sequestosome 1 deficiency accelerates osteoclastogenesis in vitro and leads to Paget's disease-like bone phenotypes in mice.
P2860
Q26796458-940D9206-2C85-4E64-8C17-97B70D80802DQ33385264-1529CFEF-5B06-4D04-88E5-B3E319C0520BQ34574123-EB83FDDB-36D4-4290-ADC2-0B09642B87B3Q34801426-CB85AF31-6E1D-4769-836C-18F160E9363CQ36155975-94BF4933-C0CD-487B-99A6-B97CA205D370Q36692317-42FFDF40-DE89-4019-90B3-3F6B6C9A3168Q36967966-CD98E01C-89EE-4D0E-84C9-D5C29043E765Q37435119-C3F12D08-4215-4E39-98A5-29C2A56AD901Q37980487-9C650839-D260-470B-A7C4-949959868B9EQ38217924-234CDFA4-818D-41A4-9C5E-3C1BA70DBAC0Q38554818-ACA61AAE-B66E-48EF-9DA2-1BF93C27DE2BQ52673130-8498860B-CA3A-42F0-9152-66349DD9CF88Q55173910-77D53725-3F49-40A9-AF4B-22A469CAD319
P2860
Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structural and functional stud ...... cause Paget's disease of bone
@ast
Structural and functional stud ...... cause Paget's disease of bone
@en
Structural and functional stud ...... cause Paget's disease of bone
@nl
type
label
Structural and functional stud ...... cause Paget's disease of bone
@ast
Structural and functional stud ...... cause Paget's disease of bone
@en
Structural and functional stud ...... cause Paget's disease of bone
@nl
prefLabel
Structural and functional stud ...... cause Paget's disease of bone
@ast
Structural and functional stud ...... cause Paget's disease of bone
@en
Structural and functional stud ...... cause Paget's disease of bone
@nl
P2093
P50
P356
P1476
Structural and functional stud ...... cause Paget's disease of bone
@en
P2093
P W Sheppard
S H Ralston
P304
P356
10.1042/BST0320728
P407
P577
2004-11-01T00:00:00Z