Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids
about
The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulatorModelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerasesIdentification, characterization, and crystal structure of the Omega class glutathione transferasesChloride and other anions inhibit dichloroacetate-induced inactivation of human liver GSTZ1 in a haplotype-dependent manner.Physiologically based pharmacokinetic modeling of dibromoacetic acid in F344 rats.Database analysis and gene discovery in pharmacogenetics.Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism.Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1.Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferasesApplying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.Glutathione s-transferases in pediatric cancer.The use of glutathione transferase-knockout mice as pharmacological and toxicological models.Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice.Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression.Functional classification and biochemical characterization of a novel rho class glutathione S-transferase in Synechocystis PCC 6803Preliminary X-ray crystallographic analysis of glutathione transferase zeta 1 (GSTZ1a-1a).Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique.Cold sensitivity in rice (Oryza sativa L.) is strongly correlated with a naturally occurring I99V mutation in the multifunctional glutathione transferase isoenzyme GSTZ2.Model Informed Dose Optimization of Dichloroacetate for the Treatment of Congenital Lactic Acidosis in Children.Developmental roles of tyrosine metabolism enzymes in the blood-sucking insect Rhodnius prolixus.Effect of short-term drinking water exposure to dichloroacetate on its pharmacokinetics and oral bioavailability in human volunteers: a stable isotope study.
P2860
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P2860
Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@ast
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@en
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@nl
type
label
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@ast
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@en
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@nl
prefLabel
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@ast
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@en
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@nl
P2093
P356
P1476
Glutathione transferase zeta-c ...... acid and other alpha-haloacids
@en
P2093
P304
P356
10.1021/TX980144F
P407
P577
1998-11-01T00:00:00Z