Ruthenium half-sandwich complexes bound to protein kinase Pim-1
about
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitorPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersSimilar Biological Activities of Two Isostructural Ruthenium and Osmium ComplexesStructure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and SelectivityExtremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF KinaseDefinite coordination arrangement of organometallic palladium complexes accumulated on the designed interior surface of apo-ferritinStructure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3βA ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome coreStructurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase InhibitorsFlexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding ModesProtein crystal structures with ferrocene and ruthenocene-based enzyme inhibitorsAn Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine TriphosphataseBioactive cyclometalated phthalimides: design, synthesis and kinase inhibitionNon-ATP-Mimetic Organometallic Protein Kinase InhibitorPIM1 kinase as a target for cancer therapyPim kinase inhibitors: a survey of the patent literatureInsights into protein kinase regulation and inhibition by large scale structural comparisonIn vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancerSynthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.In vitro evaluation of dihydropyridine-3-carbonitriles as potential cytotoxic agents through PIM-1 protein kinase inhibition.Ruthenium-based chemotherapeutics: are they ready for prime time?A metal-based inhibitor of NEDD8-activating enzyme.Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors.The ins and outs of selective kinase inhibitor development.Synthesis and cyclometalation of a pyrido[3,2-e]-2,10b-diaza-cyclopenta[c]fluorene-1,3-dione scaffold.Engineered proteins: redox properties and their applications.Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites.Synthesis of cyclopentadienyl ruthenium complexes bearing pendant chelating picolinates through an electrophilic precursor.New trends for metal complexes with anticancer activityBioorganometallic chemistry--from teaching paradigms to medicinal applications.Application of metal coordination chemistry to explore and manipulate cell biology.From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors.PIM kinases as therapeutic targets against advanced melanoma.Why target PIM1 for cancer diagnosis and treatment?Organometallic compounds: an opportunity for chemical biology?Insights from Pim1 structure for anti-cancer drug design.Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends.
P2860
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P2860
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@ast
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@en
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@nl
type
label
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@ast
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@en
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@nl
prefLabel
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@ast
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@en
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@nl
P2093
P356
P1476
Ruthenium half-sandwich complexes bound to protein kinase Pim-1
@en
P2093
Alex N Bullock
Douglas S Williams
G Ekin Atilla
Howard Bregman
Judit E Debreczeni
P304
P356
10.1002/ANIE.200503468
P407
P577
2006-02-27T00:00:00Z