High concentration of zinc in sub-retinal pigment epithelial deposits
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Therapeutic targets in age-related macular diseaseAbundant lipid and protein components of drusenApolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration.The complexities underlying age-related macular degeneration: could amyloid beta play an important role?Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitroThe oral iron chelator deferiprone protects against iron overload-induced retinal degenerationLevels of aqueous humor trace elements in patients with non-exsudative age-related macular degeneration: a case-control studyLong term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study.Biologically targeted probes for Zn(2+): a diversity oriented modular "click-SNAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the EZinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration.Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins.Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eyeComparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina degenerations.Effects of antioxidant components of AREDS vitamins and zinc ions on endothelial cell activation: implications for macular degenerationLight-induced retinal degeneration is prevented by zinc, a component in the age-related eye disease study formulationOcular manifestations of Alzheimer's disease in animal models.How does the macula protect itself from oxidative stress?The stoichiometric transition from Zn6Cu1-metallothionein to Zn7-metallothionein underlies the up-regulation of metallothionein (MT) expression: quantitative analysis of MT-metal load in eye cells.Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy.Zinc-induced self-association of complement C3b and Factor H: implications for inflammation and age-related macular degeneration.Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration.Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model.Recent advances in the understanding of the role of zinc in ocular tissues.Metallothioneins (MTs) in the human eye: a perspective article on the zinc-MT redox cycle.Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands.One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina.The mucolipin-1 (TRPML1) ion channel, transmembrane-163 (TMEM163) protein, and lysosomal zinc handling.The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD.MicroXRF tomographic visualization of zinc and iron in the zebrafish embryo at the onset of the hatching period.X-ray fluorescence microscopic measurement of elemental distribution in the mouse retina with age.Light-induced photoreceptor and RPE degeneration involve zinc toxicity and are attenuated by pyruvate, nicotinamide, or cyclic light.Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 miceSemenogelins in the human retina: Differences in distribution and content between AMD and normal donor tissues.Drusen characterization with multimodal imaging.Enhanced Detection of Sub-Retinal Pigment Epithelial Cell Layer Deposits in Human and Murine Tissue: Imaging Zinc as a Biomarker for Age-Related Macular Degeneration (An American Ophthalmological Society Thesis).CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation.A benzimidazole-based chemodosimeter for the fluorometric detection of Zn and Cu via 1,5 proton shifts and C-N bond cleavage.Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration.Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions.
P2860
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P2860
High concentration of zinc in sub-retinal pigment epithelial deposits
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
High concentration of zinc in sub-retinal pigment epithelial deposits
@ast
High concentration of zinc in sub-retinal pigment epithelial deposits
@en
High concentration of zinc in sub-retinal pigment epithelial deposits
@nl
type
label
High concentration of zinc in sub-retinal pigment epithelial deposits
@ast
High concentration of zinc in sub-retinal pigment epithelial deposits
@en
High concentration of zinc in sub-retinal pigment epithelial deposits
@nl
prefLabel
High concentration of zinc in sub-retinal pigment epithelial deposits
@ast
High concentration of zinc in sub-retinal pigment epithelial deposits
@en
High concentration of zinc in sub-retinal pigment epithelial deposits
@nl
P2093
P1476
High concentration of zinc in sub-retinal pigment epithelial deposits
@en
P2093
Alan C Bird
Christopher J Frederickson
David H Linkous
Frederik J G M van Kuijk
Jane M Flinn
Katherine Cano
Tünde Peto
P304
P356
10.1016/J.EXER.2006.12.015
P407
P577
2007-04-01T00:00:00Z