Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
about
Regulation of cell death by transfer RNACrystal structure of Onconase at 1.1 Å resolution - insights into substrate binding and collective motionLinked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivoModern Technologies for Creating Synthetic Antibodies for Clinical application.Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients.A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation.The cytotoxic ribonuclease onconase targets RNA interference (siRNA).Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.Ribonucleases as potential modalities in anticancer therapyActivating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase.Stability and folding of amphibian ribonuclease A superfamily members in comparison with mammalian homologues.Isolation of a ribonuclease with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from Japanese large brown buckwheat seeds.Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.Cell-free protein synthesis of a cytotoxic cancer therapeutic: Onconase production and a just-add-water cell-free system.A cytotoxic ribonuclease reduces the expression level of P-glycoprotein in multidrug-resistant cell lines.Onconase cytotoxicity relies on the distribution of its positive charge.tRNA binds to cytochrome c and inhibits caspase activation.Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.Oxidative folding pathway of onconase, a ribonuclease homologue: insight into oxidative folding mechanisms from a study of two homologues.Humane anesthesia and pain management in amphibian limb surgery of Rana pipiens.Interaction of onconase with the human ribonuclease inhibitor protein.Cytosolic delivery of large proteins using nanoparticle-stabilized nanocapsules.Silencing an inhibitor unleashes a cytotoxic enzyme.Site-selective azide incorporation into endogenous RNase A via a "chemistry" approach.Lp16-PSP, a Member of YjgF/YER057c/UK114 Protein Family Induces Apoptosis and p21WAF1/CIP1 Mediated G1 Cell Cycle Arrest in Human Acute Promyelocytic Leukemia (APL) HL-60 Cells.Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells.The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.
P2860
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P2860
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@ast
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@en
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@nl
type
label
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@ast
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@en
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@nl
prefLabel
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@ast
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@en
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@nl
P2860
P1476
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes
@en
P2093
P2860
P304
P356
10.2174/138920108784567245
P407
P577
2008-06-01T00:00:00Z