Antidepressant-like pharmacological profile of a novel triple reuptake inhibitor, (1S,2S)-3-(methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol (PRC200-SS)
about
Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.Current investigational drugs for major depressionEmerging targets for antidepressant therapiesEffects of the triple reuptake inhibitor amitifadine on extracellular levels of monoamines in rat brain regions and on locomotor activitySKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activityThe noradrenergic action in antidepressant treatments: pharmacological and clinical aspectsPharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.Design and synthesis of 4-heteroaryl 1,2,3,4-tetrahydroisoquinolines as triple reuptake inhibitors.Stereoselective synthesis of β-hydroxy enamines, aminocyclopropanes, and 1,3-amino alcohols via asymmetric catalysis.Psychopharmacology Today: Where are We and Where Do We Go From Here?Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents.Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressantsTriple reuptake inhibitors as potential next-generation antidepressants: a new hope?Polycyclic compounds: ideal drug scaffolds for the design of multiple mechanism drugs?Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model.Triple reuptake inhibitors for treating subtypes of major depressive disorder: the monoamine hypothesis revisited.Triple monoamine uptake inhibitors.Regioselective alkylation of 1,3,4,5-tetrahydrobenzo[d]azepin-2-one and biological evaluation of the resulting alkylated products as potentially selective [Formula: see text] agonists.Monoaminergic Antidepressants in the Relief of Pain: Potential Therapeutic Utility of Triple Reuptake Inhibitors (TRIs).
P2860
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P2860
Antidepressant-like pharmacological profile of a novel triple reuptake inhibitor, (1S,2S)-3-(methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol (PRC200-SS)
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@ast
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@en
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@nl
type
label
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@ast
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@en
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@nl
prefLabel
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@ast
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@en
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@nl
P2093
P356
P1476
Antidepressant-like pharmacolo ...... -phenylpropan-1-ol (PRC200-SS)
@en
P2093
Alfredo Oliveros
Amanda M Shaw
Elliott Richelson
Eric Blazar
Jessica Robinson
Katrina Williams
Mona Boules
Siobhan Briody
Yanqi Liang
Yiqun Zhang
P304
P356
10.1124/JPET.108.143610
P407
P577
2008-11-01T00:00:00Z