Cloning and expression of a cDNA encoding a novel human neurotrophic factor
about
trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificitiesFunction and evolution in the NGF family and its receptorsBinding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkCAn extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.Construction of a eukaryotic expression plasmid for human retina-derived neurotrophin-3.Two conserved domains in the NGF propeptide are necessary and sufficient for the biosynthesis of correctly processed and biologically active NGF.Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth.Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiationNeurotrophins promote the survival and development of neurons in the cerebellum of hypothyroid rats in vivo.Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systems.Coexpression of neurotrophins and their receptors in neurons of the central nervous system.Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation.Pathophysiological mechanisms for actions of the neurotrophins.Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.Peptides other than the neurotrophins that can be cleaved from proneurotrophins: a neglected story.Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment.The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.Alteration of NH2-terminal residues of nerve growth factor affects activity and Trk binding without affecting stability or conformation.p75 reduces TrkB tyrosine autophosphorylation in response to brain-derived neurotrophic factor and neurotrophin 4/5.Neurotrophic factors in the tongue: expression patterns, biological activity, relation to innervation and studies of neurotrophin knockout mice.Purification and characterisation of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer.Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factorDifferential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.Production and characterization of recombinant mouse neurotrophin-3.Comparison of mammalian, chicken and Xenopus brain-derived neurotrophic factor coding sequences.Rapid phosphorylation of phospholipase C gamma 1 by brain-derived neurotrophic factor and neurotrophin-3 in cultures of embryonic rat cortical neurons.Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish.Brain-derived neurotrophic factor is more highly conserved in structure and function than nerve growth factor during vertebrate evolution.Gene sequences of chicken BDNF and NT-3.Neurotrophin-3 receptors in the developing chicken retina.Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum.Development of brain-derived neurotrophic factor and neurotrophin-3 immunoreactivity in the lower auditory brainstem of the postnatal gerbil.Differential expression of brain-derived neurotrophic factor and neurotrophin 3 mRNA in lingual papillae and taste buds indicates roles in gustatory and somatosensory innervation.
P2860
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P2860
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@ast
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@en
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@nl
type
label
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@ast
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@en
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@nl
prefLabel
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@ast
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@en
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@nl
P2093
P2860
P1433
P1476
Cloning and expression of a cDNA encoding a novel human neurotrophic factor
@en
P2093
P2860
P304
P356
10.1016/0014-5793(90)81536-W
P407
P577
1990-06-18T00:00:00Z