Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas - Wikidata - wikimedia - TriplyDB

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

http://www.wikidata.org/entity/Q28292747

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Epigenetic down-regulation of the tumor suppressor gene PRDM1/Blimp-1 in diffuse large B cell lymphomas: a potential role of the microRNA let-7 The genetic landscape of diffuse large B-cell lymphoma Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma.Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.Role of MYC in B Cell Lymphomagenesis.Oncogenic activation of NF-kappaB.Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies.New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function.Analysis of the coding genome of diffuse large B-cell lymphoma MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas.Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma.PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL Differential micro-RNA expression in primary CNS and nodal diffuse large B-cell lymphomas Development and characterization of a novel human Waldenström macroglobulinemia cell line: RPCI-WM1, Roswell Park Cancer Institute - Waldenström Macroglobulinemia 1.An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.PRDM1 is a tumor suppressor gene in natural killer cell malignancies.Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications.Hypermethylation of the tumor suppressor gene PRDM1/Blimp-1 supports a pathogenetic role in EBV-positive Burkitt lymphoma.Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma.Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas HACE1 is a tumor suppressor gene candidate in natural killer cell neoplasms Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma.The molecular biology of diffuse large B-cell lymphoma.Diffuse large B-cell lymphoma: a heterogeneous group of non-Hodgkin lymphomas comprising several distinct clinicopathological entities.EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation.MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas.Cancer genetics of epigenetic genes.PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.Cell-specific transduction of Prdm1-expressing lineages mediated by a receptor for avian leukosis virus subgroup B Whole-exome sequencing identifies variants in invasive pituitary adenomas.Recent prognostic factors in diffuse large B-cell lymphoma indicate NF-kappaB pathway as a target for new therapeutic strategies.IRF4: Immunity. Malignancy! Therapy?New insights into the regulation of human B-cell differentiation.Whole-exome and transcriptome sequencing of refractory diffuse large B-cell lymphoma.

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P2860

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

http://www.wikidata.org/entity/Q28292747

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Mutational analysis of PRDM1 i ...... diffuse large B-cell lymphomas

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Amy Chadburn

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Daniel M Knowles

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Joong W Lee

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