GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development
about
Differentiation of insulin-producing cells from human neural progenitor cellsRegulation of GDF-11 and myostatin activity by GASP-1 and GASP-2GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cellsRegulation of muscle growth by multiple ligands signaling through activin type II receptors.Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatinConditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitusReversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cellsEffects of activin A on survival, function and gene expression of pancreatic islets from non-diabetic and diabetic human donorsStructural basis for potency differences between GDF8 and GDF11.Redundancy of myostatin and growth/differentiation factor 11 functionHuman pluripotent stem cells: an emerging model in developmental biology.Primary cilia in pancreatic development and disease.METABOLIC FUNCTIONS OF MYOSTATIN AND GDF11.Bone Morphogenetic Protein (BMP) signaling in development and human diseasesBiochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future InvestigationIs Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?A mouse model for monitoring islet cell genesis and developing therapies for diabetesExtracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass.A soluble activin receptor type IIB does not improve blood glucose in streptozotocin-treated miceThe Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.Wnt signaling regulates pancreatic beta cell proliferationZac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.Differential synthesis and action of TGFß superfamily ligands in mouse and rat isletsIdentification and expansion of pancreatic stem/progenitor cells.Intraislet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells.Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitorsSmad signaling pathways regulate pancreatic endocrine development.Current cell-based approaches for the treatment of diabetes mellitus.On the origin of the beta cell.Through thick and thin: a circulating growth factor inhibits age-related cardiac hypertrophy.The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in miceStem cells to pancreatic beta-cells: new sources for diabetes cell therapyA smad signaling network regulates islet cell proliferationPancreas cell fate.Heterochronic Pellet Assay to Test Cell-cell Communication in the Mouse Retina.Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
P2860
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P2860
GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@ast
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@en
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@nl
type
label
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@ast
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@en
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@nl
prefLabel
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@ast
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@en
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@nl
P2093
P921
P356
P1433
P1476
GDF11 modulates NGN3+ islet pr ...... iation in pancreas development
@en
P2093
Asa A Apelqvist
Douglas H Osborne
Erin B Harmon
Nora G Smart
Seung K Kim
Xueying Gu
P304
P356
10.1242/DEV.01535
P407
P577
2004-12-01T00:00:00Z