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A central role for free heme in the pathogenesis of severe sepsis

A central role for free heme in the pathogenesis of severe sepsis

http://www.wikidata.org/entity/Q28294459

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Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis Beyond killing: Can we find new ways to manage infection?Hepatocytes: a key cell type for innate immunity Addressing the Complications of Ebola and Other Viral Hemorrhagic Fever Infections: Using Insights from Bacterial and Fungal Sepsis Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders Disease tolerance as a defense strategy Natural history of the bruise: formation, elimination, and biological effects of oxidized hemoglobin Pharmacogenomics of human P450 oxidoreductase Nephroprotective Potential of Human Albumin Infusion: A Narrative Review The Macrophage Mediates the Renoprotective Effects of Endotoxin Preconditioning Differential Function of Lip Residues in the Mechanism and Biology of an Anthrax Hemophore Oxidative stress and the homeodynamics of iron metabolism Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases The social network of carbon monoxide in medicine Extracellular Hb enhances cardiac toxicity in endotoxemic guinea pigs: protective role of haptoglobin.Association between haptoglobin, hemopexin and mortality in adults with sepsis Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine.Host Iron Nutritional Immunity Induced by a Live Yersinia pestis Vaccine Strain Is Associated with Immediate Protection against Plague.Metabolic Adaptation Establishes Disease Tolerance to Sepsis Hormesis and Defense of Infectious Disease.Methaemoglobin and COHb in patients with malaria HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.Hemolysis-induced lethality involves inflammasome activation by heme Clinical significance of soluble hemoglobin scavenger receptor CD163 (sCD163) in sepsis, a prospective study.Diagnostic value of urine sCD163 levels for sepsis and relevant acute kidney injury: a prospective study Prevalence and gene characteristics of antibodies with cofactor-induced HIV-1 specificity.Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial.Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation.Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.Mechanisms of acute kidney injury induced by experimental Lonomia obliqua envenomation.DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock Hemopexin in severe inflammation and infection: mouse models and human diseases Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease.Hemolysis and cell-free hemoglobin drive an intrinsic mechanism for human disease.Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage.Biliary tract external drainage increases the expression levels of heme oxygenase-1 in rat livers Heme oxygenase-1 promotes the persistence of Leishmania chagasi infection Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism.

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P2860

A central role for free heme in the pathogenesis of severe sepsis

http://www.wikidata.org/entity/Q28294459

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

A central role for free heme in the pathogenesis of severe sepsis

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A central role for free heme in the pathogenesis of severe sepsis

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A central role for free heme in the pathogenesis of severe sepsis

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type

label

A central role for free heme in the pathogenesis of severe sepsis

@ast

A central role for free heme in the pathogenesis of severe sepsis

@en

A central role for free heme in the pathogenesis of severe sepsis

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prefLabel

A central role for free heme in the pathogenesis of severe sepsis

@ast

A central role for free heme in the pathogenesis of severe sepsis

@en

A central role for free heme in the pathogenesis of severe sepsis

@nl

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Science Translational Medicine

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A central role for free heme in the pathogenesis of severe sepsis

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André M Japiassú

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Angelo Chora

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Ann Smith

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Dolores Bonaparte

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Fernando A Bozza

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Ivo Marguti

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László Tokaji

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Moisés Marinho Cavalcante

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Rasmus Larsen

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Viktória Jeney

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P2860

Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigation

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells

HMG-1 as a late mediator of endotoxin lethality in mice

The epidemiology of sepsis in the United States from 1979 through 2000

Origin and physiological roles of inflammation

The immunopathogenesis of sepsis

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Miguel P. Soares

Sílvia Cardoso

Raffaella Gozzelino

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