CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis - Wikidata - wikimedia - TriplyDB

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

http://www.wikidata.org/entity/Q28295777

about

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling CD28 and CTLA-4 coreceptor expression and signal transduction Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signalling.Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.An enigmatic tail of CD28 signaling.CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response CD28 co-signaling in the adaptive immune response.Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family Five Layers of Receptor Signaling in γδ T-Cell Differentiation and Activation Regulation of interferon-gamma, interleukin-4 and interleukin-2 by Schizonepeta tenuifolia through differential effects on nuclear factor-kappaB, NFATc2 and STAT4/6.CD28 Costimulation: From Mechanism to Therapy.TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Dynamic regulation of CD28 conformation and signaling by charged lipids and ions.Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.Defects in regulatory T cells due to CD28 deficiency induce a qualitative change of allogeneic immune response in chronic graft-versus-host disease.Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation.CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study.

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P2860

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

http://www.wikidata.org/entity/Q28295777

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@ast

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@en

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@nl

type

label

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@ast

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@en

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@nl

prefLabel

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@ast

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@en

CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@nl

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International Immunology

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CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis

@en

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Hidehiro Kishimoto

http://www.w3.org/2001/XMLSchema#string

Kazunari Tanabe

http://www.w3.org/2001/XMLSchema#string

Kazunobu Onuki

http://www.w3.org/2001/XMLSchema#string

Kei Takeda

http://www.w3.org/2001/XMLSchema#string

Ryo Abe

http://www.w3.org/2001/XMLSchema#string

Ryosuke Watanabe

http://www.w3.org/2001/XMLSchema#string

Saori Kagaya

http://www.w3.org/2001/XMLSchema#string

Shuhei Ogawa

http://www.w3.org/2001/XMLSchema#string

Yohsuke Harada

http://www.w3.org/2001/XMLSchema#string

Yuu Inutake

http://www.w3.org/2001/XMLSchema#string

P2860

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling

CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.

CARMA1 is required for Akt-mediated NF-kappaB activation in T cells.

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation

P304

1507-15

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scholarly article

P356

10.1093/INTIMM/DXN108

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

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2008-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18829987

http://www.w3.org/2001/XMLSchema#string

P921