mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis - Wikidata - wikimedia - TriplyDB

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

http://www.wikidata.org/entity/Q28296765

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mTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis The TORC2 component, Sin1, controls migration of anterior mesendoderm during zebrafish gastrulation RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors Where is mTOR and what is it doing there?A systematic analysis of a mi-RNA inter-pathway regulatory motif MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4 RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients.Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways.Rictor is an independent prognostic factor for endometrial carcinoma.Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.Conditional astroglial Rictor overexpression induces malignant glioma in mice MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1.The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells.Association of PKCζ expression with clinicopathological characteristics of breast cancer.Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer.Review series: TOR kinase complexes and cell migration.The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer.Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.mTOR complex 2 signaling and functions Fission Yeast SCYL1/2 Homologue Ppk32: A Novel Regulator of TOR Signalling That Governs Survival during Brefeldin A Induced Stress to Protein Trafficking.Single-nucleotide polymorphism in microRNA-binding site of SULF1 target gene as a protective factor against the susceptibility to breast cancer: a case-control study.Defining the Domain Arrangement of the Mammalian Target of Rapamycin Complex Component Rictor Protein.Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2 PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65.Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy.Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis.mTORC2 mediates CXCL12-induced angiogenesis Interactome analysis reveals that C1QBP (complement component 1, q subcomponent binding protein) is associated with cancer cell chemotaxis and metastasis.Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis.mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.Upregulation of RICTOR gene transcription by the proinflammatory cytokines through NF-κB pathway contributes to the metastasis of renal cell carcinoma.Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway.mTOR regulate EMT through RhoA and Rac1 pathway in prostate cancer.Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer.

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P2860

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

http://www.wikidata.org/entity/Q28296765

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@ast

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@en

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@nl

type

label

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@ast

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@en

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@nl

prefLabel

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@ast

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@en

mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

@nl

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0008-5472.CAN-10-0207

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Cancer Research

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mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis

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P2093

Bin Zhang

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Hua Guo

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Menghui Li

http://www.w3.org/2001/XMLSchema#string

Ning Zhang

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Peng Chen

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Wenfeng Cao

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Xiaofang Zhang

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Xishan Hao

http://www.w3.org/2001/XMLSchema#string

Xiying Wei

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Xuchen Cao

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9360-70

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scholarly article

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1562167

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10.1158/0008-5472.CAN-10-0207

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22

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20978191

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