Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation
about
Cancer metabolism and oxidative stress: Insights into carcinogenesis and chemotherapy via the non-dihydrofolate reductase effects of methotrexateDetermination of phosphate-activated glutaminase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry)From Krebs to clinic: glutamine metabolism to cancer therapy.Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.Glutaminolysis and autophagy in cancermiR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma.Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines.Stress eating and tuning out: cancer cells re-wire metabolism to counter stress.The Pasteur's Dictum: Nitrogen Promotes Growth and Oxygen Reduces the Need for Sugar.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.Glutaminolysis as a target for cancer therapy.Inhibiting CD146 by its Monoclonal Antibody AA98 Improves Radiosensitivity of Cervical Cancer Cells.A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.Glutamine Addiction In Gliomas.Glutamine Metabolism in Cancer: Understanding the Heterogeneity.Glutaminase 2 expression is associated with regional heterogeneity of 5-aminolevulinic acid fluorescence in glioblastoma.Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancerCD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions.The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction.Glutamine Metabolism in Gliomas.Targeting Glutamine Metabolism for Cancer Treatment.Inhibition of Glycolysis and Glutaminolysis: Emerging Drug Discovery Approach to Combat Cancer.Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status.
P2860
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P2860
Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@ast
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@en
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@nl
type
label
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@ast
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@en
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@nl
prefLabel
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@ast
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@en
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@nl
P2093
P3181
P1476
Knock-down of glutaminase 2 ex ...... l cancer to ionizing radiation
@en
P2093
Ganfeng Xie
Houjie Liang
Jianfang Chen
Jianjun Li
Lisha Xiang
Songtao Yu
Xueli Pang
P304
P3181
P356
10.1016/J.BBAMCR.2013.08.003
P407
P577
2013-12-01T00:00:00Z