The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
about
The role of orphanin FQ/nociceptin in neuroplasticity: relationship to stress, anxiety and neuroinflammation.Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the ratDesigning bifunctional NOP receptor-mu opioid receptor ligands from NOP-receptor selective scaffolds. Part II.Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats.Roles of μ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates.Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in miceThe therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.Sex differences in opioid analgesia and addiction: interactions among opioid receptors and estrogen receptors.The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors.Where do we stand in the field of anti-abuse drug discovery?Targeting multiple opioid receptors - improved analgesics with reduced side effects?Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.Limited potential of cebranopadol to produce opioid-type physical dependence in rodents.A novel and selective nociceptin receptor (NOP) agonist (1-(1-((cis)-4-isopropylcyclohexyl)piperidin-4-yl)-1H-indol-2-yl)methanol (AT-312) decreases acquisition of ethanol-induced conditioned place preference in mice.Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors.Proof-of-Concept Study to Assess the Nociceptin Receptor Antagonist LY2940094 as a New Treatment for Alcohol Dependence.
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P2860
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
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2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@ast
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@en
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
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type
label
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@ast
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@en
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
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The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
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The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
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The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@nl
P2860
P1476
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications
@en
P2093
Nurulain T Zaveri
P2860
P304
P356
10.2174/156802611795371341
P407
P577
2011-01-01T00:00:00Z