Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
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Decoding the phosphorylation code in Hedgehog signal transductionDynamic interpretation of hedgehog signaling in the Drosophila wing discSonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothenedProtein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tubeA dual-kinase mechanism for Wnt co-receptor phosphorylation and activationCostal2 functions as a kinesin-like protein in the hedgehog signal transduction pathwayA novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cellsCapping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase AInhibition of the nuclear import of cubitus interruptus by roadkill in the presence of strong hedgehog signal.Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling.USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localizationHedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila.Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus.Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila.Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling.The role of kinases in the Hedgehog signalling pathway.Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activatorActivation of heterotrimeric G proteins by Smoothened.The contributions of protein kinase A and smoothened phosphorylation to hedgehog signal transduction in Drosophila melanogaster.Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responsesRegulation of smoothened by Drosophila G-protein-coupled receptor kinases.A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptusThe extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.A screen for X-linked mutations affecting Drosophila photoreceptor differentiation identifies Casein kinase 1α as an essential negative regulator of wingless signaling.RACK1 promotes non-small-cell lung cancer tumorigenicity through activating sonic hedgehog signaling pathwayFused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulationPI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail.Hedgehog secretion and signal transduction in vertebrates.Regulation of Hedgehog signaling by ubiquitination.Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.Molecular Characterization of Bovine SMO Gene and Effects of Its Genetic Variations on Body Size Traits in Qinchuan Cattle (Bos taurus).Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.Sequential phosphorylation of smoothened transduces graded hedgehog signaling.A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts.Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.Smoothened regulation in response to Hedgehog stimulation.Small-molecule modulators of Hh and Wnt signaling pathways.Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms.Hedgehog in the Drosophila testis niche: what does it do there?
P2860
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P2860
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@ast
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@en
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@nl
type
label
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@ast
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@en
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@nl
prefLabel
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@ast
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@en
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@nl
P2093
P2860
P3181
P356
P1433
P1476
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
@en
P2093
Andrew Tomlinson
Daniel Kalderon
Natalya M Katanayeva
Sergey Apionishev
Steven A Marks
P2860
P2888
P3181
P356
10.1038/NCB1210
P407
P577
2005-01-01T00:00:00Z
P6179
1038346063