Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons - Wikidata - wikimedia - TriplyDB

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

http://www.wikidata.org/entity/Q28298056

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Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model Adenosine signaling and function in glial cells Molecular dissection of reactive astrogliosis and glial scar formation Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis Stem cell therapy for autism Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological Disorders Adeno Associated Viral Vector Delivered RNAi for Gene Therapy of SOD1 Amyotrophic Lateral Sclerosis Neuroinflammation in motor neuron disease The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease Charcot-Marie-Tooth disease and intracellular traffic Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury Astrocytes conspire with neurons during progression of neurological disease Astrocytes: the missing link in neurologic disease?Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis Stem cell transplantation for motor neuron disease: current approaches and future perspectives The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS)Precursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injury Genetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type C Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy Therapeutic neuroprotective agents for amyotrophic lateral sclerosis Stem cells in the nervous system An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation Genetic correction of human induced pluripotent stem cells from patients with spinal muscular atrophy.Targeted ablation of oligodendrocytes triggers axonal damage Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.Astrocytes: biology and pathology Inhibitory synaptic regulation of motoneurons: a new target of disease mechanisms in amyotrophic lateral sclerosis.Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS Targeting Glial Mitochondrial Function for Protection from Cerebral Ischemia: Relevance, Mechanisms, and the Role of MicroRNAs A perspective on stem cell modeling of amyotrophic lateral sclerosis Emerging mechanisms of molecular pathology in ALS Forward engineering neuronal diversity using direct reprogramming

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

http://www.wikidata.org/entity/Q28298056

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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type

label

Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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prefLabel

Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Nature Neuroscience

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Astrocytes expressing ALS-link ...... ctively toxic to motor neurons

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Alcmène Chalazonitis

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Diane B Re

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Hynek Wichterle

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Makiko Nagai

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Tetsuya Nagata

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Thomas M Jessell

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P2860

Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

Directed differentiation of embryonic stem cells into motor neurons

Onset and progression in inherited ALS determined by motor neurons and microglia

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

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1114733

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10.1038/NN1876

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5

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Serge Przedborski

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2007-05-01T00:00:00Z

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6392245

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1026670759

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17435755

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amyotrophic lateral sclerosis

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3799799

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