Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
about
The gene for severe combined immunodeficiency disease in Athabascan-speaking Native Americans is located on chromosome 10p.Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytesE proteins are required to activate germline transcription of the TCR Vbeta8.2 geneControlled major histocompatibility complex-T cell receptor signaling allows efficient generation of functional, antigen-specific CD8+ T cells from embryonic stem cells and thymic progenitors.Use of interleukin 7 receptor-alpha knockout donor cells demonstrates the lymphoid independence of dendritic cellsApoptosis and interleukin 7 gene expression in chronic B-lymphocytic leukemia cells.Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants.Bone marrow declines as a site of B-cell precursor differentiation with age: relationship to thymus involutionIntrathymic IL-7: the where, when, and why of IL-7 signaling during T cell developmentOsteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female miceThe effect of in vivo IL-7 deprivation on T cell maturation.Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitors.Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selectionInterleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cellsIdentification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors developWhence the intestinal intraepithelial lymphocyte?Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genesDifferential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytesInterleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibilityExpression of recombination activating genes in germinal center B cells: involvement of interleukin 7 (IL-7) and the IL-7 receptor.Treatment with Interleukin-7 Restores Host Defense against Pneumocystis in CD4+ T-Lymphocyte-Depleted Mice.Immunosenescence of ageingInterleukin 7 receptor-deficient mice lack gammadelta T cells.Paracrine influence of human perivascular cells on the proliferation of adenocarcinoma alveolar epithelial cells.The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient miceIL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors.An interleukin-2 receptor gamma chain mutation with normal thymus morphology.CD34-positive early stages of human T-cell differentiation.Expression of human recombination activating genes (RAG-1 and RAG-2) in lymphoma.Stromal cells and cytokines in the induction of recombination activating gene (RAG) expression in a human lymphoid progenitor cell.The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesisThe influence of IL-7 V(D)J recombination.JAK3 Janus kinase is involved in interleukin 7 signal pathway.Interleukin-7, a non-redundant potent cytokine whose over-expression massively perturbs B-lymphopoiesis.Interleukin-7 (IL-7) knockout mice. Implications for lymphopoiesis and organ-specific immunity.Challenges for vaccination in the elderly.Transgenic expression of interleukin 7 restores T cell populations in nude mice.Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.Scheduled kinetics of cell proliferation and phenotypic changes during immature thymocyte generation.Thymic function in the regulation of T cells, and molecular mechanisms underlying the modulation of cytokines and stress signaling (Review).
P2860
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P2860
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@ast
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@en
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@nl
type
label
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@ast
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@en
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@nl
prefLabel
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@ast
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@en
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@nl
P2093
P356
P1433
P1476
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
@en
P2093
P356
10.1126/SCIENCE.7686307
P407
P577
1993-07-02T00:00:00Z