A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis - Wikidata - wikimedia - TriplyDB

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

http://www.wikidata.org/entity/Q28298834

about

SALL4, the missing link between stem cells, development and cancer Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells Hematopoiesis "awakens": Evolving technologies, the force behind them.Leukemic survival factor SALL4 contributes to defective DNA damage repair.SALL4 promotes gastric cancer progression through activating CD44 expression Apoptotic cell: linkage of inflammation and wound healing.Optimizing autologous cell grafts to improve stem cell gene therapy.The next new target in leukemia: The embryonic stem cell gene SALL4.The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis.TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis.SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide

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A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

http://www.wikidata.org/entity/Q28298834

description

2013 nî lūn-bûn

@nan

2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

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2013年论文

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name

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@ast

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@en

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@nl

type

label

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

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A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

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A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@nl

prefLabel

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@ast

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@en

A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@nl

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Journal of Clinical Investigation

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A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis

@en

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Ailing Li

http://www.w3.org/2001/XMLSchema#string

Bee H Liu

http://www.w3.org/2001/XMLSchema#string

Chong Gao

http://www.w3.org/2001/XMLSchema#string

Donna Neuberg

http://www.w3.org/2001/XMLSchema#string

Gang Huang

http://www.w3.org/2001/XMLSchema#string

Ha-Won Jeong

http://www.w3.org/2001/XMLSchema#string

Jiayun Lu

http://www.w3.org/2001/XMLSchema#string

Li Chai

http://www.w3.org/2001/XMLSchema#string

Ping Tang

http://www.w3.org/2001/XMLSchema#string

Xiaopan Yao

http://www.w3.org/2001/XMLSchema#string

P2860

Global and Hox-specific roles for the MLL1 methyltransferase

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family

Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

Novel mutations in the gene SALL4 provide further evidence for acro-renal-ocular and Okihiro syndromes being allelic entities, and extend the phenotypic spectrum

Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy

SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

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scholarly article

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4866492

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10.1172/JCI62891

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10

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2013-09-24T00:00:00Z

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3784519

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