The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
about
Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cellsThe LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcriptionThe LIM-only protein FHL2 is a negative regulator of E4F1Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actinSerum response factor binding sites differ in three human cell typesGenome-wide analysis of transcription factor binding sites based on ChIP-Seq dataLoss of serum response factor in keratinocytes results in hyperproliferative skin disease in miceModulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activityThe LIM-only protein FHL2 attenuates lung inflammation during bleomycin-induced fibrosisThe LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cellsProline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2Neuronal migration in the murine rostral migratory stream requires serum response factor.Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells.Deficiency in the LIM-only protein Fhl2 impairs skin wound healingThe LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways.Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.Fhl2 deficiency results in osteopenia due to decreased activity of osteoblastsMyocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.Linking actin dynamics and gene transcription to drive cellular motile functions.FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer.Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB.Defining the mammalian CArGomeIdentification of FHL2-regulated genes in liver by microarray and bioinformatics analysis.FHL2 expression and variants in hypertrophic cardiomyopathy.LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasisSite-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.Gene expression analyses implicate an alternative splicing program in regulating contractile gene expression and serum response factor activity in mice.FHL2 regulates hematopoietic stem cell functions under stress conditionsIdentifying functional single nucleotide polymorphisms in the human CArGomeGene Expression Analyses during Spontaneous Reversal of Cardiomyopathy in Mice with Repressed Nuclear CUG-BP, Elav-Like Family (CELF) Activity in Heart Muscle.Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures.SMYD1, an SRF-Interacting Partner, Is Involved in Angiogenesis.Identification of Targets of CUG-BP, Elav-Like Family Member 1 (CELF1) Regulation in Embryonic Heart Muscle.Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors.Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.Transcriptional control of cardiac fibroblast plasticity.FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.Effect of destrin mutations on the gene expression profile in vivo.Regulation of myocardin factor protein stability by the LIM-only protein FHL2FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth
P2860
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P2860
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@ast
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@en
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@nl
type
label
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@ast
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@en
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@nl
prefLabel
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@ast
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@en
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@nl
P2093
P1433
P1476
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
@en
P2093
Alfred Nordheim
Christoph Dieterich
Felix B Engel
Frank Gertler
Gerhard Schratt
Judith M Müller
Mark T Keating
Petra Galgóczy
Roland Schüle
Ulrike Philippar
P304
P356
10.1016/J.MOLCEL.2004.11.039
P407
P577
2004-12-22T00:00:00Z