An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division - Wikidata - wikimedia - TriplyDB

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

http://www.wikidata.org/entity/Q28299789

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Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells.SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1 Identification of a physiological E2 module for the human anaphase-promoting complex The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome Genomic screening with RNAi: results and challenges The genomic and transcriptomic landscape of a HeLa cell line Identifying druggable disease-modifying gene products Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145 E-RNAi: a web application to design optimized RNAi constructs.Thorough validation of siRNA-induced cell death phenotypes defines new anti-apoptotic protein FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets.Systems biology of cisplatin resistance: past, present and future Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size CAR-1, a protein that localizes with the mRNA decapping component DCAP-1, is required for cytokinesis and ER organization in Caenorhabditis elegans embryos.Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells.An oncogenic role for the phosphorylated h-subunit of human translation initiation factor eIF3 Targeted comparative RNA interference analysis reveals differential requirement of genes essential for cell proliferation Deciphering protein function during mitosis in PtK cells using RNAi.Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.Son is essential for nuclear speckle organization and cell cycle progression.Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish.RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells Modelling data across labs, genomes, space and time.Complete, gene-specific siRNA libraries: production and expression in mammalian cells.Design of a genome-wide siRNA library using an artificial neural network.How will RNAi facilitate drug development?Genome-wide application of RNAi to the discovery of potential drug targets.Phenotype-based identification of host genes required for replication of African swine fever virus Enzymatically prepared RNAi libraries.Genome-wide functional analysis of human cell-cycle regulators.GenomeRNAi: a database for cell-based RNAi phenotypes.

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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

http://www.wikidata.org/entity/Q28299789

description

2004 nî lūn-bûn

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2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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An endoribonuclease-prepared s ...... es essential for cell division

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Anne-Kristin Heninger

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Bernd Korn

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Laurence Pelletier

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Maria Teresa Pisabarro

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P2860

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

RNA interference is mediated by 21- and 22-nucleotide RNAs

Role for a bidentate ribonuclease in the initiation step of RNA interference

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

A system for stable expression of short interfering RNAs in mammalian cells

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

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1036-40

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10.1038/NATURE03159

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7020

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432

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Marie-Laure Yaspo

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Heinz Himmelbauer

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2004-12-23T00:00:00Z

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1004519673

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15616564

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