Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development
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VE-PTP controls blood vessel development by balancing Tie-2 activityNew Insights into VacA Intoxication Mediated through Its Cell Surface ReceptorsRegulation of Endothelial Adherens Junctions by Tyrosine PhosphorylationSmall molecule tools for functional interrogation of protein tyrosine phosphatasesVe-ptp modulates vascular integrity by promoting adherens junction maturationBrain barriers: Crosstalk between complex tight junctions and adherens junctionsDissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivoVascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesisVE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formationFusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation.Recurrent PTPRB and PLCG1 mutations in angiosarcoma.Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesityExpression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculatureThe PI3K p110alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1.An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculatureMitogen-activated protein kinase phosphatase-1 is a key regulator of hypoxia-induced vascular endothelial growth factor expression and vessel density in lungReceptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.Hydroxyindole carboxylic acid-based inhibitors for receptor-type protein tyrosine protein phosphatase betaThe angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammationThe complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway.Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cellsUnderstanding endothelial cell apoptosis: what can the transcriptome, glycome and proteome reveal?Hypoxia-induced expression of VE-cadherin and filamin B in glioma cell cultures and pseudopalisade structuresProtein tyrosine phosphatases: functional inferences from mouse models and human diseases.Substrate specificity of R3 receptor-like protein-tyrosine phosphatase subfamily toward receptor protein-tyrosine kinases.Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progressionMicrobial induction of vascular pathology in the CNS.Tie2 is tied at the cell-cell contacts and to extracellular matrix by angiopoietin-1Deciphering the functional role of endothelial junctions by using in vivo modelsTransmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis.Regulation of vascular integrity.Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.Shear stress-induced redistribution of vascular endothelial-protein-tyrosine phosphatase (VE-PTP) in endothelial cells and its role in cell elongation.Dual roles of protein tyrosine phosphatase kappa in coordinating angiogenesis induced by pro-angiogenic factors.Phosphatase regulation of intercellular junctions.VE-cadherin: at the front, center, and sides of endothelial cell organization and function.
P2860
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P2860
Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Vascular endothelial cell-spec ...... d for blood vessel development
@ast
Vascular endothelial cell-spec ...... d for blood vessel development
@en
Vascular endothelial cell-spec ...... d for blood vessel development
@nl
type
label
Vascular endothelial cell-spec ...... d for blood vessel development
@ast
Vascular endothelial cell-spec ...... d for blood vessel development
@en
Vascular endothelial cell-spec ...... d for blood vessel development
@nl
prefLabel
Vascular endothelial cell-spec ...... d for blood vessel development
@ast
Vascular endothelial cell-spec ...... d for blood vessel development
@en
Vascular endothelial cell-spec ...... d for blood vessel development
@nl
P2093
P50
P3181
P1433
P1476
Vascular endothelial cell-spec ...... d for blood vessel development
@en
P2093
Alexander Gamp
Astrid Holtmann
Linda Keller
Ruth Funke
P304
P3181
P356
10.1182/BLOOD-2006-01-0141
P407
P50
P577
2006-06-15T00:00:00Z