STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum
about
Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases.Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal FunctionInhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medicationsNeuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemiaInhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's diseaseExtrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEPTranslation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulationThe striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdalaSynaptic plasticity: one STEP at a time.Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disordersStriatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwayOxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61.Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP.Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP.The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation.Taking STEPs forward to understand fragile X syndrome.The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.A common STEP in the synaptic pathology of diverse neuropsychiatric disorders.Rapid regulation of endoplasmic reticulum dynamics in dendritic spines by NMDA receptor activation.Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity.Use of Peptides for the Management of Alzheimer's Disease: Diagnosis and Inhibition.
P2860
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P2860
STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@ast
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@en
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@nl
type
label
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@ast
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@en
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@nl
prefLabel
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@ast
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@en
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@nl
P2093
P3181
P1476
STEP61: a member of a family o ...... d to the endoplasmic reticulum
@en
P2093
M Solimena
P J Lombroso
P304
P3181
P356
10.1523/JNEUROSCI.16-24-07821.1996
P407
P577
1996-12-01T00:00:00Z