X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility - Wikidata - wikimedia - TriplyDB

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

http://www.wikidata.org/entity/Q28301018

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IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation Regulation of Cell Death by IAPs and Their Antagonists Survivin - The inconvenient IAP Small-molecule SMAC mimetics as new cancer therapeutics Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)IAP regulation of metastasis.E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton.LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.Interaction of CSR1 with XIAP reverses inhibition of caspases and accelerates cell death Effects of bevacizumab in mouse model of endometrial cancer: Defining the molecular basis for resistance.Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells.The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth.The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)Small-molecule pan-IAP antagonists: a patent review.Chaperone-assisted degradation: multiple paths to destruction.Targeting inhibitor of apoptosis proteins for therapeutic intervention.Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists.IAPs on the move: role of inhibitors of apoptosis proteins in cell migration.AZD5582, an IAP antagonist that leads to apoptosis in head and neck squamous cell carcinoma cell lines and is eligible for combination with irradiation.Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer.Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins.XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling.Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.Ubiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray.The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms Ubiquitin-dependent regulation of Cdc42 by XIAP.A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation.IAPs as E3 ligases of Rac1: shaping the move.Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner.X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.Divide and rule: The role of ubiquitination in inactivation of the ERK5-MAPK cascade.

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X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

http://www.wikidata.org/entity/Q28301018

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@ast

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@en

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@nl

type

label

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@ast

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@en

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@nl

prefLabel

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@ast

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@en

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@nl

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Nature Cell Biology

P1476

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

@en

P2093

Christiaan Karreman

http://www.w3.org/2001/XMLSchema#string

Emad S Alnemri

http://www.w3.org/2001/XMLSchema#string

Gregory S Harms

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Krishnaraj Rajalingam

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Mirko Hekman

http://www.w3.org/2001/XMLSchema#string

Taner Dogan

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Tripat Kaur Oberoi

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Ulf R Rapp

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P2860

A novel role for XIAP in copper homeostasis through regulation of MURR1

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

Regulation of cell motility by mitogen-activated protein kinase

Targeting RAS signalling pathways in cancer therapy

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

MAP kinase signalling pathways in cancer

Pathways of chaperone-mediated protein folding in the cytosol

IAP proteins: blocking the road to death's door

The RAF proteins take centre stage

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10.1038/NCB1804

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12

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10

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2008-12-01T00:00:00Z

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232778002

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1017925206

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19011619

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