An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis - Wikidata - wikimedia - TriplyDB

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis

http://www.wikidata.org/entity/Q28301787

about

Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Occupational and genetic risk factors for osteoarthritis: a review Mechanisms for asporin function and regulation in articular cartilage A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity The biology of small leucine-rich proteoglycans in bone pathophysiology Strategic applications of gene expression: from drug discovery/development to bedside Matrix control of transforming growth factor-β function Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment Meta-analysis of association between the ASPN D-repeat and osteoarthritis Expression and regulation of the osteoarthritis-associated protein asporin TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis.Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.Association of a functional microsatellite within intron 1 of the BMP5 gene with susceptibility to osteoarthritis.Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis.Extracellular matrix molecules: potential targets in pharmacotherapy.Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis Genetic, clinical and radiographic signs in knee osteoarthritis susceptibility.Identification of novel keloid biomarkers through profiling of tissue biopsies versus cell cultures in keloid margin specimens compared to adjacent normal skin.Genetic effects of rs3740199 polymorphism in ADAM12 gene on knee osteoarthritis: a meta-analysis.IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration.Association study of candidate genes for susceptibility to Kashin-Beck disease in a Tibetan population The Good the Bad and the Ugly of Glycosaminoglycans in Tissue Engineering Applications A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis Evaluating the clinical relevance of codon 594 (g>a) polymorphism of estrogen receptor alpha in knee osteoarthritis.UDP xylose synthase 1 is required for morphogenesis and histogenesis of the craniofacial skeleton.The biomechanical characteristics of the bone-periodontal ligament-cementum complex An integrated proteomics analysis of bone tissues in response to mechanical stimulation

P2860

Q21092908-4BC7BA79-4151-46B9-9D30-83B2F63558BB Q21195662-D8146014-909C-437A-A7B7-2BAFFEEE7A2A Q21710680-13109007-93D9-4AA9-B11A-BA9FE381BB2B Q23924562-1DDB6813-4F13-4E20-9E83-05FCB1D214ED Q24293079-8616E072-796D-401B-8CF0-0E6D3787B8FD Q24301216-27895825-856C-4B2D-8D65-EAAB47D349B5 Q24312183-0D935975-DE22-463F-A990-E3C3CE3082FE Q24812968-1EFFB67B-B0F3-414B-9B0F-83F1AEEBFFBC Q26861290-C8F941FA-B2E0-4AFA-8BC9-0969B2FA6ED5 Q26864172-42A32E72-E64C-4734-BCEA-DA092CCA32F4 Q27002535-D267427F-EC54-4B10-A614-286348A9999A Q27312679-36214BD5-CF69-41D1-B31F-058158FDBF37 Q28211169-F519B92F-3F3B-4F04-9E2F-90DC620BA3E4 Q28246205-3A00B54C-D0DB-480D-9DE0-454ECE7625C0 Q28302484-7A9E3C0B-4133-4290-96B9-7804530FCBB5 Q28474080-755F980C-C86E-4D50-8686-8C07711C036E Q28504614-5C2BF84B-04A0-4133-AC14-0257BE862A35 Q28512681-CA85585B-8027-41C7-A820-745A289CDEDB Q28547683-CC8ACC71-3E1D-41E7-AA6C-27C5A53BF4F1 Q30450699-7EB9C19E-7DAB-4D08-A27C-95CDD6EB6849 Q33264597-A5F4BB61-A4D9-4702-A6C8-191E3643C639 Q33280165-09D273F5-2459-423A-B8F1-A6B00A59D669 Q33346368-22E8814D-BB7F-4821-ADFC-61FD858A8CD3 Q33519752-F156C6E9-A94E-4F92-B893-E78FA4E6401D Q33538895-3CC7265B-6823-4DE5-BED3-5B986161DF8E Q33543752-67B2DCB4-FAE7-4A9F-A0A9-8CFF410845A0 Q33597165-F96C5BC3-DFF2-4D2F-A86D-3EB7FC1CF78E Q33694487-DF01321D-BF36-48A7-B1DE-4430D7240F82 Q33760068-8FC8E069-3E7C-4A3C-929C-C0CBBD609380 Q33765713-3C08318C-40D7-4B35-B65E-417A8215540A Q33775215-BC127E71-7626-4C6A-9657-D9E9E350B879 Q33823843-6F8381CF-5D17-4938-BD49-C9DA990432BB Q33830162-47BE8ABC-3432-435F-ACB9-FB3A75EF79F2 Q33837445-C02246F2-5E27-4B5F-A213-30278F3E9865 Q33851544-C2275E45-AE34-4E69-A078-4EF883575372 Q33873604-0E9768A0-8DA7-4D68-8204-5B4AF8BFF191 Q33886483-F8B7177F-1AEC-463C-B30F-8EC6964C57F7 Q33922775-97E8ADF1-961F-49B8-875A-9B597CC480DB Q34077975-07B633D4-D00E-45E2-995D-C87686624ECA Q34333581-31529967-6FED-44F0-B069-5D3440303A78

P2860

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis

http://www.wikidata.org/entity/Q28301787

description

2005 nî lūn-bûn

@nan

2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@ast

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@en

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@nl

type

label

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@ast

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@en

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@nl

prefLabel

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@ast

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@en

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@nl

P1433

Q28301787-D07601EE-4ADB-40B9-800C-945E25904545

P1476

Q28301787-E08E173C-6DAB-4E21-8E93-E645DA7F2CDE

P2093

Q28301787-08E7E774-0896-4891-8B4B-1EF7CCA858C3

Q28301787-0C95AB09-E2A7-4FE9-A52C-9E1BF5918CA1

Q28301787-28214B92-28D4-402C-BEA4-970AA8C7C775

Q28301787-2A5ECC53-0B99-4103-A2FC-6FE3954BACB3

Q28301787-382FDB51-6841-4ADE-97FD-678E11E58037

Q28301787-4E928E2C-A8E2-42D3-8F51-0F6AF964E064

Q28301787-7C7FAEFE-358F-4A17-BFB3-3C52B1FA5CAA

Q28301787-9297DBE2-FCB3-42C4-9192-02FC27E7D484

Q28301787-9EB01728-0E5D-44A1-98C7-BC7B7A533E0E

Q28301787-A1F63FB3-1623-4E1F-AA2F-639C7170F51E

P2860

Q28301787-13B5C1C1-A427-4D43-B66F-5A4D3093D40F

Q28301787-165D7287-3C86-4B73-B490-9A97E9C0E3F8

Q28301787-1BED4F29-39BD-4292-A697-639D8A9CCED2

Q28301787-2B336381-0502-4866-AADB-531570E8BA76

Q28301787-2FE56346-33D4-4966-87AF-F5848C658F93

Q28301787-38F7F0A9-CC2C-4168-8F94-F01256833E02

Q28301787-3C48E26D-FDE9-4B61-A906-64F164D6AE94

Q28301787-49D992C0-0B4B-4F65-902D-E119F55D0A3C

Q28301787-544FB4B7-649F-4963-BD90-8003F2E2C6CE

Q28301787-565D9E07-1034-4531-9209-BE19701D5F40

P2888

Q28301787-56509A3E-5A4E-4BD4-A60E-933415478F97

P304

Q28301787-DD8AB95A-544D-4233-83CD-F2F6E43990E9

P31

Q28301787-628E80AD-D0FC-4856-9084-92CC2688C89A

P3181

Q28301787-2807C5CE-8FE6-4D91-B949-37BA39B2C449

P356

Q28301787-DB963995-7F57-41C2-8E97-CE8133F2819D

P407

Q28301787-6A7B8460-6AC3-41A8-A263-A59D11CCBA46

P433

Q28301787-E5F744A4-5C16-48C0-B778-B845F8F2B35B

P478

Q28301787-359E8957-3EE3-4A96-B1E4-3BF89851675D

P577

Q28301787-2FA1EF15-44EA-42CF-8498-78EC1D5BC864

P5875

Q28301787-A87F88DA-276F-4F38-85EA-D08990A28D9D

P698

Q28301787-474BC4B2-7377-49F3-8249-E9206FB4E2D4

P921

Q28301787-6B363B44-F0AC-4CDF-A237-B535288F3C51

P3181

P356

P1433

Nature Genetics

P1476

An aspartic acid repeat polymo ...... sceptibility to osteoarthritis

@en

P2093

Akihiko Mabuchi

http://www.w3.org/2001/XMLSchema#string

Akihiro Kotani

http://www.w3.org/2001/XMLSchema#string

Akihiro Sudo

http://www.w3.org/2001/XMLSchema#string

Akira Fukuda

http://www.w3.org/2001/XMLSchema#string

Akira Kawakami

http://www.w3.org/2001/XMLSchema#string

Aritoshi Iida

http://www.w3.org/2001/XMLSchema#string

Atsumasa Uchida

http://www.w3.org/2001/XMLSchema#string

Hideki Kizawa

http://www.w3.org/2001/XMLSchema#string

Ikuyo Kou

http://www.w3.org/2001/XMLSchema#string

Kohei Notoya

http://www.w3.org/2001/XMLSchema#string

P2860

Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta

Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan

Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

Identification of sequence polymorphisms in two sulfation-related genes, PAPSS2 and SLC26A2, and an association analysis with knee osteoarthritis

Radiological assessment of osteo-arthrosis

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

GENETIC FACTORS IN GENERALIZED OSTEO-ARTHROSIS

Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibilit

Genetic epidemiology of primary osteoarthritis.

P2888

P304

138-44

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1296051

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NG1496

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

37

http://www.w3.org/2001/XMLSchema#string

P577

2005-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8090141

http://www.w3.org/2001/XMLSchema#string

P698

15640800

http://www.w3.org/2001/XMLSchema#string

P921