Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity - Wikidata - wikimedia - TriplyDB

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

http://www.wikidata.org/entity/Q28302291

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CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands Orphan endogenous lipids and orphan GPCRs: a good match Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)EBI2 mediates B cell segregation between the outer and centre follicle The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment.The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues.Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptors EBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail.Assessment of constitutive activity of a G protein-coupled receptor, CPR2, in Cryptococcus neoformans by heterologous and homologous methods.A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans Intercellular Lipid Mediators and GPCR Drug Discovery Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses.GPR18 in microglia: implications for the CNS and endocannabinoid system signalling Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?Oxysterol-EBI2 signaling in immune regulation and viral infection.Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.The future of antiviral immunotoxins.Biased agonism and allosteric modulation of G protein-coupled receptor 183 - a 7TM receptor also known as Epstein-Barr virus-induced gene 2.Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats.Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.Epstein-Barr Virus-induced Gene 2 and Leukocyte Airway Recruitment in Response to Allergen Challenge.Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells.Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways.EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation.Unique interaction pattern for a functionally biased ghrelin receptor agonist.Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6 The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages.Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23-dependent murine model.GPR183 binds 7alpha;25-dihydroxycholesterol

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Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

http://www.wikidata.org/entity/Q28302291

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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type

label

Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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prefLabel

Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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Molecular pharmacological phen ...... tor with constitutive activity

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P3181

P356

P1433

Journal of Biological Chemistry

P1476

Molecular pharmacological phen ...... tor with constitutive activity

@en

P2093

Hans R Lüttichau

http://www.w3.org/2001/XMLSchema#string

Helene Andersen

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Jørgen K Larsen

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Tau Benned-Jensen

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Thomas N Kledal

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P2860

Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

Human B cells immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5

Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection

The G protein-coupled receptor repertoires of human and mouse

High constitutive signaling of the ghrelin receptor--identification of a potent inverse agonist

Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors

Common structural basis for constitutive activity of the ghrelin receptor family

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

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13199-208

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scholarly article

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1729689

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10.1074/JBC.M602245200

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19

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281

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Jan Pravsgaard Christensen

Peter Johannes Holst

Thue W Schwartz

Mette M. Rosenkilde

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2006-05-12T00:00:00Z

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7239122

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16540462

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P921

transmembrane protein