Medulloblastoma: developmental mechanisms out of control
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TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behaviorMedulloblastoma stem cells: Promising targets in medulloblastoma therapyThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaZfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium FunctionMicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastomaMultiple recurrent genetic events converge on control of histone lysine methylation in medulloblastomaCerebellum development and medulloblastomaDevelopment and cancer of the cerebellumYAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationThe primary cilium: a signalling centre during vertebrate developmentVMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells.A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse modelPolycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion.Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer.MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence.Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliationIdentification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer.Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells.XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Deregulated proliferation and differentiation in brain tumors.Sonic hedgehog-induced histone deacetylase activation is required for cerebellar granule precursor hyperplasia in medulloblastoma.Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome.WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation.Vimentin and Notch as biomarkers for breast cancer progressionGene expression by simian virus 40 large T antigen-induced medulloblastomas in mice.Isolation of distinct cell populations from the developing cerebellum by microdissection.Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastomaOncogenesis and cancer stem cells: current opinions and future directions.Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity.Genetic and molecular alterations across medulloblastoma subgroupsGlioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of the nichePost-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma developmentCTNNB1, AXIN1 and APC expression analysis of different medulloblastoma variants.Epigenetic Silencing of DKK3 in medulloblastoma.Treatment of pediatric brain tumors.Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma
P2860
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P2860
Medulloblastoma: developmental mechanisms out of control
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Medulloblastoma: developmental mechanisms out of control
@ast
Medulloblastoma: developmental mechanisms out of control
@en
Medulloblastoma: developmental mechanisms out of control
@nl
type
label
Medulloblastoma: developmental mechanisms out of control
@ast
Medulloblastoma: developmental mechanisms out of control
@en
Medulloblastoma: developmental mechanisms out of control
@nl
prefLabel
Medulloblastoma: developmental mechanisms out of control
@ast
Medulloblastoma: developmental mechanisms out of control
@en
Medulloblastoma: developmental mechanisms out of control
@nl
P3181
P1476
Medulloblastoma: developmental mechanisms out of control
@en
P2093
Silvia Marino
P3181
P356
10.1016/J.MOLMED.2004.11.008
P407
P577
2005-01-01T00:00:00Z