A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic
about
Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranesPonsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctionsNectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing proteinA role for Sec1/Munc18 proteins in platelet exocytosisMunc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cellsInsulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2Novel isoform of syntaxin 1 is expressed in mammalian cellsNeurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formationAfadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionUltrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situSyntaxin binding mechanism and disease-causing mutations in Munc18-2Mso1p: a yeast protein that functions in secretion and interacts physically and genetically with Sec1p.A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuoleSyntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulationAQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18bMunc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cellsNexilin: a novel actin filament-binding protein localized at cell-matrix adherens junctionMunc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles.The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells.Munc18-1 and Munc18-2 proteins modulate beta-cell Ca2+ sensitivity and kinetics of insulin exocytosis differently.Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membraneAssociations among types of impulsivity, substance use problems and neurexin-3 polymorphisms.Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A.Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sampleCharacterization of gene expression in resting and activated mast cells.Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells.Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1.Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes.Munc18c in adipose tissue is downregulated in obesity and is associated with insulinCab45b, a Munc18b-interacting partner, regulates exocytosis in pancreatic beta-cells.Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells.Morphological docking of secretory vesicles.The role of Munc18-1 and its orthologs in modulation of cortical F-actin in chromaffin cells.The SNARE Machinery in Mast Cell Secretion.Definition of a minimal munc18c domain that interacts with syntaxin 4Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion.Glutamate enhances the surface distribution and release of Munc18 in cerebral cortical neuronsEndogenous syntaxins 2, 3 and 4 exhibit distinct but overlapping patterns of expression at the hepatocyte plasma membrane.Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse.MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development.
P2860
Q21092770-FA75819B-3DD8-4125-A9B4-64BE93613791Q22009075-6465A01C-5A7E-4AFB-92AB-8032E6283CA9Q22009475-3E97A256-5427-4D8C-AE36-C0860647E5BDQ24303397-82F62876-55B3-43E4-8A9B-19DC28325240Q24313947-E7163812-C7D6-4596-AA54-99C4AC611AB0Q24316504-90A61446-83C8-477A-BBD6-1E1492E17F23Q24530022-B54654C8-9C7E-4070-AA24-36F25630292DQ24678330-361ECD6C-A673-41F4-98D2-0314E85C2A68Q24678766-B63761B7-270D-4ED2-948C-D84218D019C3Q26269856-41AC3182-E4BB-4904-8A7B-832B72D24977Q27680537-F6E6AC0E-4DBA-4CF4-A85F-9073A1BBF997Q27932792-A647635F-387A-4C87-94D0-5E6F99CAAA60Q27938441-6F97B675-92F2-4642-B8F2-C50FA2E82AEDQ28513189-7BB867F2-ACFC-4FA1-9C7A-1CF21ED7C148Q28513896-7A2A6145-663E-4DDA-923E-B541EBB560C4Q28570408-594F775C-CDB1-4F4A-B1F6-8267FC5FC46BQ28571541-7290D51D-563B-4C7C-980C-816B7930CAD9Q33961324-8EB926C6-B8DD-4B6A-81AA-755CEAAE70AEQ34148225-56671451-4462-42FA-AAD7-4C87BAABA45EQ35150073-15B1EA42-660A-4BDA-B36C-A5D3F1BE4802Q35475108-D474F6EB-3473-417C-8EA0-0C27FCB848A1Q35661896-3B76CA1A-BFD0-4DCB-841D-BDA3B3AE6ED5Q35741009-94C57113-59E4-4A62-96C1-0CC1C243154CQ36341076-705258DB-D6E5-408D-A82A-516DB06707AFQ36401747-74D49381-1CE1-42E9-9F7B-C700C851901FQ36438819-B1846BC8-2949-4E96-8C05-0DBE74444C5CQ36456714-794217C2-4640-4582-B645-224B209F7CCCQ36685019-785860BE-244F-40AE-B11F-B6CE52C0BEB8Q36859379-21E72D37-BE00-4AE6-83EB-1286B90D0240Q37344046-87CC2AE0-83DD-4BF0-B7E3-87551F397E45Q37448299-88BE8759-7C57-4263-AEDE-41EC762FF484Q37767629-987C1565-F18E-4330-A8A8-7CE48AE3A3B3Q38005609-EB5861C9-2347-497F-88A9-B37D14301C85Q38017191-4E489582-3594-4A89-AC3B-8C0B5BB9D8E0Q38308721-8973468D-FED1-457B-A8ED-3F7BD417A87DQ38420628-2BD6F813-5C8E-4ED3-9B50-519189625C47Q41351622-3FB93B95-991C-4F31-A18E-DC278EA849A8Q42159466-F0C31DDB-E216-48E1-BC98-776584C9E7ECQ43100218-A64E969E-20C5-4401-A2D3-E301E9539895Q47108329-87B84A8A-0ED4-4436-A30E-54551121D2F9
P2860
A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@ast
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@en
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@nl
type
label
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@ast
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@en
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@nl
prefLabel
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@ast
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@en
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@nl
P1476
A novel ubiquitous form of Mun ...... s involved in membrane traffic
@en
P2093
P304
P407
P577
1995-06-02T00:00:00Z