The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles
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Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseThe structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylationMolecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipBCrystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9Novel Molecular Markers for Breast CancerCyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV TatStructural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2Molecular basis of differential selectivity of cyclobutyl-substituted imidazole inhibitors against CDKs: insights for rational drug designDrug targets for cell cycle dysregulators in leukemogenesis: in silico docking studiesMultiple mechanisms determine the order of APC/C substrate degradation in mitosis.Cyclin E-dependent protein kinase activity regulates niche retention of Drosophila ovarian follicle stem cells.Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding.Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21Centrosomal localization of cyclins E and A: structural similarities and functional differencesPolyphony: superposition independent methods for ensemble-based drug discovery.Insights on Structural Characteristics and Ligand Binding Mechanisms of CDK2Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongationA transcriptome-based model of central memory CD4 T cell death in HIV infection.ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages.Comparative Analysis of the Effects of Two Probiotic Bacterial Strains on Metabolism and Innate Immunity in the RAW 264.7 Murine Macrophage Cell Line.Novel 4-(4-substituted-thiazol-2-ylamino)-N-(pyridin-2-yl)-benzenesulfonamides as cytotoxic and radiosensitizing agents.Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding.Post-translational modification and stability of low molecular weight cyclin E.Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycleCovalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression.Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2.NDGA-P21, a novel derivative of nordihydroguaiaretic acid, inhibits glioma cell proliferation and stemness.PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing.Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase.Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.Structural insights into the functional diversity of the CDK-cyclin family
P2860
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P2860
The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@ast
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@en
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@nl
type
label
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@ast
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@en
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@nl
prefLabel
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@ast
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@en
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@nl
P2093
P2860
P356
P1433
P1476
The structure of cyclin E1/CDK ...... ion and CDK2-independent roles
@en
P2093
Edward D Lowe
Elena Dubinina
Louise N Johnson
Nick R Brown
Reiko Honda
Vicky Skamnaki
P2860
P304
P356
10.1038/SJ.EMBOJ.7600554
P407
P577
2005-01-20T00:00:00Z