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Inactivating CUX1 mutations promote tumorigenesis

Inactivating CUX1 mutations promote tumorigenesis

http://www.wikidata.org/entity/Q28303563

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Rare Cytogenetic Abnormalities and Alteration of microRNAs in Acute Myeloid Leukemia and Response to Therapy The utility of transposon mutagenesis for cancer studies in the era of genome editing.In silico identification of potential key regulatory factors in smoking-induced lung cancer.The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways.Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway Controlled expression of Drosophila homeobox loci using the Hostile takeover system.The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation.Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer.A landscape of pharmacogenomic interactions in cancer.Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence Germline large genomic alterations on 7q in patients with multiple primary cancers.Leishmania (Leishmania) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism.ZRF1 is a novel S6 kinase substrate that drives the senescence programme.Processed pseudogenes acquired somatically during cancer development.-7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity.Therapy-related myeloid neoplasms: when genetics and environment collide.A population-based analysis of germline BAP1 mutations in melanoma.Inversion of chromosome 7q22 and q36 as a sole abnormality presenting in myelodysplastic syndrome: a case report.Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans.Universal Patterns of Selection in Cancer and Somatic Tissues.Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.Mutations in myeloproliferative neoplasms - their significance and clinical use.Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia.Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies may not always be associated with therapy-related myeloid neoplasms

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Inactivating CUX1 mutations promote tumorigenesis

http://www.wikidata.org/entity/Q28303563

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Inactivating CUX1 mutations promote tumorigenesis

@ast

Inactivating CUX1 mutations promote tumorigenesis

@en

Inactivating CUX1 mutations promote tumorigenesis

@nl

type

label

Inactivating CUX1 mutations promote tumorigenesis

@ast

Inactivating CUX1 mutations promote tumorigenesis

@en

Inactivating CUX1 mutations promote tumorigenesis

@nl

prefLabel

Inactivating CUX1 mutations promote tumorigenesis

@ast

Inactivating CUX1 mutations promote tumorigenesis

@en

Inactivating CUX1 mutations promote tumorigenesis

@nl

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Nature Genetics

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Inactivating CUX1 mutations promote tumorigenesis

@en

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Charles E Massie

http://www.w3.org/2001/XMLSchema#string

Chi C Wong

http://www.w3.org/2001/XMLSchema#string

Christina Kober

http://www.w3.org/2001/XMLSchema#string

Constantine Alifrangis

http://www.w3.org/2001/XMLSchema#string

David J Adams

http://www.w3.org/2001/XMLSchema#string

Inigo Martincorena

http://www.w3.org/2001/XMLSchema#string

Jessamy C Tiffen

http://www.w3.org/2001/XMLSchema#string

Jyoti Nangalia

http://www.w3.org/2001/XMLSchema#string

Mamunur Rashid

http://www.w3.org/2001/XMLSchema#string

Peter J Campbell

http://www.w3.org/2001/XMLSchema#string

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An integrated map of genetic variation from 1,092 human genomes

PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein

Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain protein

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

dbSNP: the NCBI database of genetic variation

Melanoma genome sequencing reveals frequent PREX2 mutations

ARID1A mutations in endometriosis-associated ovarian carcinomas

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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33-8

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scholarly article

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4638673

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10.1038/NG.2846

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1

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46

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Ultan McDermott

Ludmil B. Alexandrov

Elli Papaemmanuil

Alistair G Rust

Anthony R Green

Hartmut Döhner

Konstanze Döhner

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2014-01-01T00:00:00Z

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259850628

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24316979

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3874239

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