Effects of recombinant agouti-signaling protein on melanocortin action
about
The mouse mahogany locus encodes a transmembrane form of human attractinNovel binding motif of ACTH analogues at the melanocortin receptorsInteraction of Agouti protein with the melanocortin 1 receptor in vitro and in vivoLiver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetesMutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2The mahogany protein is a receptor involved in suppression of obesityThe yellow mouse obesity syndrome and mechanisms of agouti-induced obesity.Melanocortin-3 receptors and metabolic homeostasis.Genetic studies of the mouse mutations mahogany and mahoganoid.Agouti revisited: transcript quantification of the ASIP gene in bovine tissues related to protein expression and localization.Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice.Genetic and biochemical studies of the Agouti-attractin system.Agouti-related protein segments outside of the receptor binding core are required for enhanced short- and long-term feeding stimulationThe melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.The MC4 receptor and control of appetite.Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists.Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti.Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.A polymorphism in the agouti signaling protein gene is associated with human pigmentation.Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor.Minireview: the melanocortin 2 receptor accessory proteins.Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling.γ₂-Melanocyte stimulation hormone (γ₂-MSH) truncation studies results in the cautionary note that γ₂-MSH is not selective for the mouse MC3R over the mouse MC5R.Structural insight into the role of the human melanocortin 3 receptor cysteine residues on receptor function.Contribution of the transmembrane domain 6 of melanocortin-4 receptor to peptide [Pro5, DNal (2')8]-gamma-MSH selectivity.The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface.Functional properties of an agouti signaling protein variant and characteristics of its cognate radioligand.Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade.Antagonist and agonist activities of the mouse agouti protein fragment (91-131) at the melanocortin-1 receptor.Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist PharmacologAgouti Signaling Protein and Its Receptors as Potential Molecular Markers for Intramuscular and Body Fat Deposition in Cattle.
P2860
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P2860
Effects of recombinant agouti-signaling protein on melanocortin action
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Effects of recombinant agouti-signaling protein on melanocortin action
@ast
Effects of recombinant agouti-signaling protein on melanocortin action
@en
Effects of recombinant agouti-signaling protein on melanocortin action
@nl
type
label
Effects of recombinant agouti-signaling protein on melanocortin action
@ast
Effects of recombinant agouti-signaling protein on melanocortin action
@en
Effects of recombinant agouti-signaling protein on melanocortin action
@nl
prefLabel
Effects of recombinant agouti-signaling protein on melanocortin action
@ast
Effects of recombinant agouti-signaling protein on melanocortin action
@en
Effects of recombinant agouti-signaling protein on melanocortin action
@nl
P2093
P356
P1476
Effects of recombinant agouti-signaling protein on melanocortin action
@en
P2093
B D Wilson
C Dickinson
M M Ollmann
P304
P356
10.1210/MEND.11.3.9898
P407
P577
1997-03-01T00:00:00Z