The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
about
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complexRelaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathwaysIn a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR FamilySolution structure of a conformationally restricted fully active derivative of the human relaxin-like factorSplice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexityRegulation of receptor signaling by relaxin A chain motifs: derivation of pan-specific and LGR7-specific human relaxin analogsThe relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxinIdentification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay.Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane.Investigation of interactions at the extracellular loops of the relaxin family peptide receptor 1 (RXFP1).International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.The minimal active structure of human relaxin-2The structural determinants of insulin-like Peptide 3 activityThe different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin.Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes.The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1Relaxin family peptides: structure-activity relationship studies.The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8.
P2860
Q24293265-48E4FDAE-E667-4948-B52B-DED1ABD2C665Q24564959-4DEB20D3-1EC6-417E-A0ED-280FD38D35EDQ26781446-F2D7B3C0-282C-4213-A7E3-95A4DD8F3004Q27653164-D7A41279-DC5F-4D2E-9816-0F2078EF8584Q28264243-5DC2FFA2-FC08-4DDC-ADE0-C51E7C1886E5Q28756592-4467664B-A8A2-4980-AF05-3447DC25D125Q30352669-99C95922-8756-45E5-9CCB-3FDA56DFB7BBQ30369442-CF11641B-3CFF-4E5A-A890-D33D0A2C1110Q33774441-7E48F9AF-0520-43DA-98B5-D9ED4E76A4BAQ33789816-A794B2C7-E585-479A-93B8-A7DED1CE8F1FQ34501476-DA781166-3CDE-4D53-A3D4-5C6A19A801B3Q34551052-17061885-5B5B-428B-A040-EC90A3122815Q34559725-7630A58F-0D60-48B0-A39C-A8E6F6650171Q34683416-A101B4C9-77EF-4C15-96C9-AAFB6F34DC03Q35383835-6B1CFEAD-3AFE-4C9E-91AE-FC1EB0E04ADCQ35423895-25984DF8-9415-4B19-BA90-B9BD9C5C9D09Q35972135-33882905-914B-4F94-A284-80E327CBA7F1Q36367155-82747B27-E02D-4B2E-BF26-E416C2E1DDAEQ36436057-09137E67-779A-40CF-B7D7-5825AAF9F93EQ36509796-879CCE7E-5684-47FB-B234-06319E2121ACQ36815189-58215225-1AE7-4A17-9706-E67B2151A639Q39030385-9DE4DD2D-D52D-4060-A598-3537234C2FCAQ40255208-9E50F5D7-AACA-46AF-88E5-D042554B3A22
P2860
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@ast
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@en
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@nl
type
label
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@ast
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@en
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@nl
prefLabel
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@ast
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@en
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@nl
P2860
P3181
P356
P1476
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
@en
P2093
Christian Schwabe
Erika E Büllesbach
P2860
P304
P3181
P356
10.1074/JBC.M500030200
P407
P577
2005-04-08T00:00:00Z