Control of mammalian cochlear amplification by chloride anions
about
Prestin's anion transport and voltage-sensing capabilities are independentAnion control of voltage sensing by the motor protein prestin in outer hair cellsConformational state-dependent anion binding in prestin: evidence for allosteric modulationPrestin and the cochlear amplifierRegulation of electromotility in the cochlear outer hair cellSalicylate-induced cochlear impairments, cortical hyperactivity and re-tuning, and tinnitus.Modelling cochlear mechanics.Chloride Anions Regulate Kinetics but Not Voltage-Sensor Qmax of the Solute Carrier SLC26a5.Current carried by the Slc26 family member prestin does not flow through the transporter pathway.Optogenetic Control of Mouse Outer Hair Cells.The chloride-channel blocker 9-anthracenecarboxylic acid reduces the nonlinear capacitance of prestin-associated charge movement.An electrical inspection of the subsurface cisternae of the outer hair cell.Chloride-driven electromechanical phase lags at acoustic frequencies are generated by SLC26a5, the outer hair cell motor protein.Reduction in noise-induced functional loss of the cochleae in mice with pre-existing cochlear dysfunction due to genetic interference of prestin.Extracellular chloride regulation of Kv2.1, contributor to the major outward Kv current in mammalian outer hair cells.Salicylate-induced auditory perceptual disorders and plastic changes in nonclassical auditory centers in rats.Identifying tinnitus-related genes based on a side-effect network analysis.Prestin regulation and function in residual outer hair cells after noise-induced hearing loss.Progress in cochlear physiology after BékésyAnalgesic use and the risk of hearing loss in women.Disparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5.Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochleaNormal hearing sensitivity at low-to-middle frequencies with 34% prestin-charge densityCoupling active hair bundle mechanics, fast adaptation, and somatic motility in a cochlear model.Prestin-based outer hair cell electromotility in knockin mice does not appear to adjust the operating point of a cilia-based amplifier.Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification.Fast electromechanical amplification in the lateral membrane of the outer hair cell.Cochlear amplification, outer hair cells and prestin.Effect of the cochlear microphonic on the limiting frequency of the mammalian ear.Sound-evoked radial strain in the hearing organ.Cysteine mutagenesis reveals transmembrane residues associated with charge translocation in prestinInteraction between CFTR and prestin (SLC26A5)Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters.Chloride and salicylate influence prestin-dependent specific membrane capacitance: support for the area motor model.Effect of salicylate on KCNQ4 of the guinea pig outer hair cell.Combinatorial cysteine mutagenesis reveals a critical intramonomer role for cysteines in prestin voltage sensingPrestin surface expression and activity are augmented by interaction with MAP1S, a microtubule-associated proteinA genetically-encoded YFP sensor with enhanced chloride sensitivity, photostability and reduced ph interference demonstrates augmented transmembrane chloride movement by gerbil prestin (SLC26a5).Ca2+ signaling in the inner ear.Cochlear perfusion with a viscous fluid.
P2860
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P2860
Control of mammalian cochlear amplification by chloride anions
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Control of mammalian cochlear amplification by chloride anions
@ast
Control of mammalian cochlear amplification by chloride anions
@en
Control of mammalian cochlear amplification by chloride anions
@nl
type
label
Control of mammalian cochlear amplification by chloride anions
@ast
Control of mammalian cochlear amplification by chloride anions
@en
Control of mammalian cochlear amplification by chloride anions
@nl
prefLabel
Control of mammalian cochlear amplification by chloride anions
@ast
Control of mammalian cochlear amplification by chloride anions
@en
Control of mammalian cochlear amplification by chloride anions
@nl
P2093
P1476
Control of mammalian cochlear amplification by chloride anions
@en
P2093
Alfred L Nuttall
Jiefu Zheng
Joseph Santos-Sacchi
P304
P356
10.1523/JNEUROSCI.4548-05.2006
P407
P577
2006-04-12T00:00:00Z