Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
about
GABA and Glutamate Transporters in BrainAmphetamine modulates excitatory neurotransmission through endocytosis of the glutamate transporter EAAT3 in dopamine neuronsMechanisms of glutamate transportThe Concise Guide to PHARMACOLOGY 2013/14: transporters.Pathophysiology of glia in perinatal white matter injury.Structure-activity-relationship study of N-acyl-N-phenylpiperazines as potential inhibitors of the Excitatory Amino Acid Transporters (EAATs): improving the potency of a micromolar screening Hit is not truism.The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.Altered astrocyte glutamate transporter regulation of hypothalamic neurosecretory neurons in heart failure rats.Chemistry and biology of multicomponent reactions.Excitatory amino acid transporters as potential drug targets.Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease.Organocatalyzed enantioselective synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates.Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs.Structure and allosteric inhibition of excitatory amino acid transporter 1.The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.Characterization of the L-glutamate clearance pathways across the blood-brain barrier and the effect of astrocytes in an in vitro blood-brain barrier model.Activation of glutamate transport evokes rapid glutamine release from perisynaptic astrocytes.Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102.
P2860
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P2860
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@ast
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@en
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@nl
type
label
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@ast
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@en
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@nl
prefLabel
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@ast
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@en
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@nl
P2093
P356
P1476
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1
@en
P2093
Christina W Nielsen
Jan Kehler
Mette N Erichsen
Tine B Stensbøl
P304
P356
10.1021/JM8013458
P407
P577
2009-02-01T00:00:00Z