GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo - Wikidata - wikimedia - TriplyDB

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

http://www.wikidata.org/entity/Q28307776

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International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands The Calcium-Sensing Receptor and Integrins in Cellular Differentiation and Migration Osteocalcin as a hormone regulating glucose metabolism Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism Multiligand specificity and wide tissue expression of GPRC6A reveals new endocrine networks Minireview: Nutrient sensing by G protein-coupled receptors X-ray Crystal Structure of Bovine 3 Glu-Osteocalcin Regulation of male fertility by the bone-derived hormone osteocalcin Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis.Novel bone endocrine networks integrating mineral and energy metabolism Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2)Osteocalcin induces release of glucagon-like peptide-1 and thereby stimulates insulin secretion in mice.GGCX and VKORC1 inhibit osteocalcin endocrine functions.Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice.Skeleton and glucose metabolism: a bone-pancreas loop.The effects of acute hyperinsulinemia on bone metabolism.Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport.Structural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral Tissues New insights into the biology of osteocalcin.GPRC6a is not required for the effects of a high-protein diet on body weight in mice GPRC6A mediates the effects of L-arginine on insulin secretion in mouse pancreatic islets.Evidence for Osteocalcin Binding and Activation of GPRC6A in β-Cells Associations of total and undercarboxylated osteocalcin with peripheral and hepatic insulin sensitivity and β-cell function in overweight adults Searching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics.Multiple faces of fibroblast growth factor-23 A systems biology preview of the relationships between mineral and metabolic complications in chronic kidney disease.In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice Protein/amino-acid modulation of bone cell function.Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.GPRC6A: Jack of all metabolism (or master of none).A crosstalk between bone and gonads.Endogenous metabolites as ligands for G protein-coupled receptors modulating risk factors for metabolic and cardiovascular disease.The GPCR, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function.Osteocalcin, energy and glucose metabolism.Bone as an endocrine organ relevant to diabetes.Osteocalcin: an osteoblast-derived polypeptide hormone that modulates whole body energy metabolism.Bone, brain & beyond.

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GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

http://www.wikidata.org/entity/Q28307776

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

@ast

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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type

label

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

@en

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

@nl

prefLabel

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

@ast

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

@en

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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Journal of Bone and Mineral Research

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GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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L Darryl Quarles

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Yunpeng Wu

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P2860

Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain

An amino-acid taste receptor

Endocrine regulation of energy metabolism by the skeleton

Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis

Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a

Identification of a novel extracellular cation-sensing G-protein-coupled receptor

Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

Klotho converts canonical FGF receptor into a specific receptor for FGF23

The metabotropic glutamate receptors: structure and functions

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

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10.1002/JBMR.390

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21425331

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Aizkuņģa dziedzeris

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5079536

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