Strand-Specific Postreplicative Processing of Mammalian Telomeres
about
Five dysfunctional telomeres predict onset of senescence in human cellsHuman UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replicationMammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cellsLoss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer CellsMammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityThe involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeresKu86 represses lethal telomere deletion events in human somatic cellsDNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptasePOT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombinationDefective DNA repair and increased genomic instability in Artemis-deficient murine cellsApollo contributes to G overhang maintenance and protects leading-end telomeresSingle strand DNA binding proteins 1 and 2 protect newly replicated telomeresSNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repairMammalian polymerase θ promotes alternative NHEJ and suppresses recombinationTelomeres and human disease: ageing, cancer and beyondYeast telomerase is specialized for C/A-rich RNA templates.Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivoPOT1 protects telomeres from a transient DNA damage response and determines how human chromosomes endDifferential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres.Multiple roles for MRE11 at uncapped telomeres.Protection and replication of telomeres in fission yeast.ATR contributes to telomere maintenance in human cellsMice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeresDNA damage-induced phosphorylation of the human telomere-associated protein TRF2.Hyper telomere recombination accelerates replicative senescence and may promote premature aging.Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines.Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in ArabidopsisTelomeres, aging and cancer: in search of a happy ending.Telomeres, chromosome instability and cancerTelomere length regulates the epigenetic status of mammalian telomeres and subtelomeres.Differential processing of leading- and lagging-strand ends at Saccharomyces cerevisiae telomeres revealed by the absence of Rad27p nuclease.
P2860
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P2860
Strand-Specific Postreplicative Processing of Mammalian Telomeres
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@ast
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@en
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@nl
type
label
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@ast
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@en
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@nl
prefLabel
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@ast
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@en
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@nl
P3181
P356
P1433
P1476
Strand-Specific Postreplicative Processing of Mammalian Telomeres
@en
P2093
S. M. Bailey
P304
P3181
P356
10.1126/SCIENCE.1062560
P407
P577
2001-09-28T00:00:00Z