Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A - Wikidata - wikimedia - TriplyDB

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

http://www.wikidata.org/entity/Q28316169

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Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-delta Topical cyclosporine A therapy for dry eye syndrome The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors Cloning and characterization of cyclophilin C-associated protein: a candidate natural cellular ligand for cyclophilin C Calcineurin functions in Ca(2+)-activated cell death in mammalian cells Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1 Development of lifitegrast: a novel T-cell inhibitor for the treatment of dry eye disease Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans Treatment of hippocampal neurons with cyclosporin A results in calcium overload and apoptosis which are independent on NMDA receptor activation Protein phosphatase inhibitors facilitate DHPG-induced LTD in the CA1 region of the hippocampus RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the alpha or beta catalytic subunit Cain, a novel physiologic protein inhibitor of calcineurin Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells.Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients.Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons.FK506 and the role of the immunophilin FKBP-52 in nerve regeneration.Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities Autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura in pediatric solid organ transplant recipients, report of five cases and review of the literature.Fluconazole plus cyclosporine: a fungicidal combination effective against experimental endocarditis due to Candida albicans.HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach An alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile.Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells Role of protein phosphatases in the regulation of human mast cell and basophil function.Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%

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P2860

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

http://www.wikidata.org/entity/Q28316169

description

1992 nî lūn-bûn

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1992 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1992 թվականի մայիսին հրատարակված գիտական հոդված

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1992年の論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年论文

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name

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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type

label

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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prefLabel

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

@ast

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

@en

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Calcineurin phosphatase activi ...... ed by FK 506 and cyclosporin A

@en

P2093

B E Bierer

http://www.w3.org/2001/XMLSchema#string

C B Klee

http://www.w3.org/2001/XMLSchema#string

D A Fruman

http://www.w3.org/2001/XMLSchema#string

S J Burakoff

http://www.w3.org/2001/XMLSchema#string

P2860

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

Protein phosphatases come of age

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.

Probing immunosuppressant action with a nonnatural immunophilin ligand.

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

Serine/threonine phosphatases in the nervous system.

P304

3686-90

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scholarly article

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885059

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P356

10.1073/PNAS.89.9.3686

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P433

9

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P478

89

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P577

1992-05-01T00:00:00Z

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21781599

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P698

1373887

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P932

525555

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