A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1
about
Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissuePractical synthesis of prostratin, DPP, and their analogs, adjuvant leads against latent HIVEmerging strategies to deplete the HIV reservoirTargeting NF-κB signaling with protein kinase C agonists as an emerging strategy for combating HIV latencyMichellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanismsMechanism of selective inhibition of human immunodeficiency virus by ingenol triacetateAn in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patientsTubulin is a molecular target of the Wnt-activating chemical probeSynergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.Making the most of Papua New Guinea's biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in "The Land of the Unexpected"Ensuring equitable benefits: the falealupo covenant and the isolation of anti-viral drug prostratin from a samoan medicinal plant.Picomolar dichotomous activity of gnidimacrin against HIV-1.De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genesA historical overview of natural products in drug discovery.Identification, activity, and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C.Stelleralides A-C, novel potent anti-HIV daphnane-type diterpenoids from Stellera chamaejasme LProtein Kinase C: One Pathway towards the Eradication of Latent HIV-1 Reservoirs.Wealth of opportunity - the C1 domain as a target for drug development.Molecular mechanisms of HIV-1 proviral latency.Biyouyanagin A, an anti-HIV agent from Hypericum chinense L. var. salicifolium.Isolation, structure determination, and anti-HIV evaluation of tigliane-type diterpenes and biflavonoid from Stellera chamaejasme.Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo.Variability in content of the anti-AIDS drug candidate prostratin in Samoan populations of Homalanthus nutans.Recent Progress of Research on Herbal Products Used in Traditional Chinese Medicine: the Herbs belonging to The Divine Husbandman's Herbal Foundation Canon ( Shén Nóng Běn Cǎo Jīng).Challenges to the development of bryostatin-type anticancer drugs based on the activation mechanism of protein kinase Cδ.Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators.Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities.Pharmaceutical potential of phorbol esters from Jatropha curcas oil.Prostratin exhibits both replication enhancing and inhibiting effects on FIV infection of feline CD4+ T-cells.Effects of prostratin on T-cell activation and human immunodeficiency virus latency.Establishment and maintenance of HIV latency: model systems and opportunities for intervention.Novel phorbol esters exert dichotomous effects on inhibition of HIV-1 infection and activation of latent HIV-1 expression.Histone deacetylase inhibitors containing a benzamide functional group and a pyridyl cap are preferentially effective human immunodeficiency virus-1 latency-reversing agents in primary resting CD4+ T cells.Analysis by fluorescence resonance energy transfer of the interaction between ligands and protein kinase Cdelta in the intact cell.Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms.Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry.How Might We Cure HIV?Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCalpha and PKCtheta.Potential anticancer effect of prostratin through SIK3 inhibition.Novel Latency Reversal Agents for HIV-1 Cure.
P2860
Q24562082-0ACE38D8-F3E4-4843-8D03-675B3970B8C6Q24654112-AD07F473-DA0B-442C-9B2D-BE226EDE6138Q27023877-8A7EFE9F-94F3-4EEE-8F95-0F242EDF2C5DQ27026631-17A523F2-4852-476F-A0A8-39AAEFAB8063Q28367673-781F4708-D2A3-4AA3-83E7-00195D134072Q28379091-22A63354-0118-42E4-8DB6-279EC2827F9DQ28538015-FA7047C8-EFD7-4ADB-A67E-2F5AB81E9F33Q28833737-E912348C-80C2-4FF8-8E4C-24928F3472BFQ33476165-682FB7AD-34FF-4108-9FE9-D7D49230EEF1Q33519039-67407C57-ECF8-4C47-9981-A078EFFCA7F7Q33893126-2DD41B88-D7B4-4BE5-B2A8-47FAF30B985EQ34062554-7C7098B4-B1B5-4B1B-99A5-9A74F094E52CQ34094578-F576EC7D-02C0-4745-92DA-FD5EC193AFFBQ34426191-DCDAC823-A26C-4CF2-8D9C-452714F82E5BQ34844607-FF25534A-25B8-439A-AEC5-E75A0A72EE1FQ35030769-4C22383E-FA51-45A2-97F0-6A84D3046AD7Q35830264-61553FCA-94A2-4B22-A659-75AFDCAE2435Q36168226-587D6AF5-7760-4897-9BB8-1C894F963479Q36278085-FC81F6A6-422B-4DDB-A1AB-8CE08896FCA7Q36925481-CA9670DD-C846-48F8-94DC-B42C4F4B48A7Q37024047-0E2CA492-3B8B-47A5-AECB-6DB3136F832BQ37031659-63A5C387-2664-44A5-A016-275394763567Q37146593-D2DFAF38-346C-481F-BA97-970BCAAA9CC9Q37618370-75C802EF-5B97-43D6-8093-209D8C5BB5F0Q38005950-603B71F5-7260-4C1F-8E79-A6FE8BB90FC0Q38213132-87010722-0D80-4952-914F-BBAF9A170350Q38917496-E121FD90-8B6E-4B37-8F57-749252ED669BQ38971339-DF9BEE58-DDBD-470D-BDD9-FB26F81725B3Q39234712-DFB75E61-4145-471C-BBC0-BB4FEAD3F2A7Q39753161-AF32899C-21AF-4498-8BEC-94E76859D7A5Q39783316-8418BFA0-74ED-4D8A-9653-DC36255C1F1CQ40358616-39AD1022-6768-4C7D-937E-343F03EA81E3Q40361855-C121CF0E-23DF-4A72-A903-98CE43CE61B5Q40478545-D0050BE0-A21C-42AE-A37A-537A584BFDE5Q40509085-F0F077E9-C79E-456E-8AAA-1C2400AF584DQ40589086-39C8B94A-7E16-4080-803B-EBBB717F73E9Q42227337-171207B8-82FB-4329-BA04-2E2DF252C6DAQ42929742-7A4F4F58-0D9E-42EF-808E-B624E74BF9FFQ50053216-A8B6D13F-23BA-4CA3-8853-C59C856945D4Q52816327-4C423A24-298A-4244-A450-5509123C778B
P2860
A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1
description
1992 nî lūn-bûn
@nan
1992 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@ast
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@en
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@nl
type
label
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@ast
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@en
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@nl
prefLabel
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@ast
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@en
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@nl
P2093
P3181
P356
P1476
A nonpromoting phorbol from th ...... inhibits cell killing by HIV-1
@en
P2093
J A Beutler
J B McMahon
J H Cardellina
J Ishitoya
K R Gustafson
O S Weislow
P M Blumberg
R J Gulakowski
Z Szallasi
P304
P3181
P356
10.1021/JM00089A006
P407
P577
1992-05-29T00:00:00Z