Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells
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(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitroThe anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosineSelective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosineBisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3'-azido-3'-deoxythymidine or 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitroInfluence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activityUnique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89Didanosine-associated eosinophilia with acute thrombocytopenia.N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutationsAntiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol.In vitro potency of inhibition by antiviral drugs of hematopoietic progenitor colony formation correlates with exposure at hemotoxic levels in human immunodeficiency virus-positive humans.Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcriptionTreatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: combination therapy.Antiviral therapy for human immunodeficiency virus infectionsZidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.Antiviral therapy: current concepts and practicesPotent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action.The anti-human immunodeficiency virus agent 3'-fluorothymidine induces DNA damage and apoptosis in human lymphoblastoid cells.The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study.Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger.The combined anti-HIV-1 activities of emtricitabine and tenofovir plus the integrase inhibitor elvitegravir or raltegravir show high levels of synergy in vitro.
P2860
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P2860
Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells
description
1991 nî lūn-bûn
@nan
1991 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@ast
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@en
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@nl
type
label
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@ast
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@en
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@nl
prefLabel
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@ast
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@en
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@nl
P2093
P2860
P356
P1476
Anti-human immunodeficiency vi ...... human marrow progenitor cells
@en
P2093
D R Averett
G W Koszalka
M H St Clair
R E Dornsife
T J Panella
P2860
P356
10.1128/AAC.35.2.322
P407
P577
1991-02-01T00:00:00Z