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Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline stateStructural basis for the oxidation of thiosulfate by a sulfur cycle enzyme.Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrinThe SoxYZ complex carries sulfur cycle intermediates on a peptide swinging armTrapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanismX-ray crystallography, mass spectrometry and single crystal microspectrophotometry: a multidisciplinary characterization of catechol 1,2 dioxygenaseStructural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutantsCO Rebinding Kinetics and Molecular Dynamics Simulations Highlight Dynamic Regulation of Internal Cavities in Human CytoglobinATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinusFrom protein structure to function via single crystal optical spectroscopySite-directed mutations of human hemoglobin at residue 35beta: a residue at the intersection of the alpha1beta1, alpha1beta2, and alpha1alpha2 interfacesHigh and low oxygen affinity conformations of T state hemoglobinStructural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.Protein crystal microspectrophotometry.Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutesFollowing ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca.Functional characterization of heme proteins encapsulated in wet nanoporous silica gels.Functional properties of the active core of human cystathionine beta-synthase crystals.Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis.Ligand migration in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana.Characterization of ligand migration mechanisms inside hemoglobins from the analysis of geminate rebinding kinetics.Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin.Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin.Polymerization of hemoglobins in Arctic fish: Lycodes reticulatus and Gadus morhua.Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions.Oxygen and nitric oxide rebinding kinetics in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana.Ligation tunes protein reactivity in an ancient haemoglobin: kinetic evidence for an allosteric mechanism in Methanosarcina acetivorans protoglobin.Heterogeneous kinetics of the carbon monoxide association and dissociation reaction to nitrophorin 4 and 7 coincide with structural heterogeneity of the gate-loop.Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins.Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin.Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers.Targeting cystalysin, a virulence factor of treponema denticola-supported periodontitis.Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria.Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivoransStructure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models.Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicusCircular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels.Correlation of protein functional properties in the crystal and in solution: the case study of T-state hemoglobin.Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
ricercatore
@it
հետազոտող
@hy
name
Stefano Bruno
@ast
Stefano Bruno
@en
Stefano Bruno
@es
Stefano Bruno
@nl
Stefano Bruno
@sl
type
label
Stefano Bruno
@ast
Stefano Bruno
@en
Stefano Bruno
@es
Stefano Bruno
@nl
Stefano Bruno
@sl
prefLabel
Stefano Bruno
@ast
Stefano Bruno
@en
Stefano Bruno
@es
Stefano Bruno
@nl
Stefano Bruno
@sl
P214
P106
P1153
7101967954
P21
P214
P31
P496
0000-0002-7890-2472
P734
P735
P7859
viaf-249863697