Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes
about
Zinc and Manduca sexta hemocyte functionsLeukotrienes in pulmonary arterial hypertensionThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humansBlocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation.Improved inhibitor screening experiments by comparative analysis of simulated enzyme progress curves.Induced protein degradation: an emerging drug discovery paradigm.A remarkable activity of human leukotriene A4 hydrolase (LTA4H) toward unnatural amino acidsLeukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296.Targeted Protein Degradation: from Chemical Biology to Drug Discovery.Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase.Ubenimex activates the E-cadherin-mediated adhesion of a breast cancer cell line YMB-S.Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.The aminopeptidase activity in the human T-cell lymphoma line (Jurkat) is not at the cell surface and is not aminopeptidase N (CD-13).Leukotriene A4 hydrolase: a critical role of glutamic acid-296 for the binding of bestatin.The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors.The human leukotriene A4 hydrolase gene is expressed in two alternatively spliced mRNA forms.A tyrosine residue essential for catalytic activity in aminopeptidase A.Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice
P2860
Q24798443-E3365A2C-BBB6-4B0F-A196-C280EB634C03Q26853496-E42DADCE-DE5F-4F35-978B-F000D0FA819FQ30486745-BFE27AF6-6B30-4AFA-B526-CE59EDFB32E4Q30495582-097DEC66-18F4-4BD6-BC2C-4ED1D3B5441FQ33593640-39CD5398-CFF3-40FF-8C2C-F2F05F2EB626Q33974854-5F67D947-BA47-4A1C-AA72-70857A9F8C7BQ34447440-E6CFB4F5-790D-479C-BFCB-37A4B4BD8A07Q34545841-08AE034C-802F-4EDB-85DE-26716DBE9C37Q35103537-923FA26D-67AD-4CA5-8E39-1F814755BC49Q37224881-8C67E4B4-BDD5-47BE-B0F4-4E4B32858634Q39396984-5A741BFF-1351-4D45-B655-F7814F12A6DFQ39643271-B831582E-2211-4CA0-829D-ED3226B36992Q41353182-321FFEF7-1F67-4AD8-98B6-5EC934B797D6Q41811713-0E6361A0-6637-4E55-B132-6DE59770B85AQ41815470-FD058195-9589-4FE0-ADBB-4CEB7125B16EQ41900212-9C75BEF3-C0D3-4D33-A35D-99306CBAC3D9Q42139297-E2CEF4B8-B55A-448F-8335-8498C4D1B5ADQ42981368-F8BF696F-5201-416B-93FE-45BE6F2B7EFAQ42988381-3C3EC1D2-EA29-4EBE-A87D-437B5B72C055Q58209773-A110CFA6-F626-4D1A-8F13-3B1CC3168C77
P2860
Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@ast
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@en
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@nl
type
label
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@ast
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@en
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@nl
prefLabel
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@ast
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@en
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@nl
P2093
P1476
Leukotriene A4 hydrolase. Inhi ...... ce to metallohydrolase enzymes
@en
P2093
F A Fitzpatrick
P304
P407
P577
1991-01-01T00:00:00Z