Drug interaction studies of a glucan synthase inhibitor (LY 303366) and a chitin synthase inhibitor (Nikkomycin Z) for inhibition and killing of fungal pathogens
about
Escape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofunginExtra copies of the Aspergillus fumigatus squalene epoxidase gene confer resistance to terbinafine: genetic approach to studying gene dose-dependent resistance to antifungals in A. fumigatusUpdate on antifungals targeted to the cell wall: focus on beta-1,3-glucan synthase inhibitors.Synergy, pharmacodynamics, and time-sequenced ultrastructural changes of the interaction between nikkomycin Z and the echinocandin FK463 against Aspergillus fumigatus.Efficacy of micafungin alone or in combination against systemic murine aspergillosis.New and emerging antifungal agents: impact on respiratory infections.Combating opportunistic infections: coccidioidomycosis.Combination treatment of invasive fungal infections.Combination antifungals: an update.Regulation of expression, activity and localization of fungal chitin synthases.Addressing current medical needs in invasive fungal infection prevention and treatment with new antifungal agents, strategies and formulations.Echinocandin resistance in Candida species: mechanisms of reduced susceptibility and therapeutic approaches.Systemic Antifungal Agents: Current Status and Projected Future Developments.The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.Experimental design and statistical analysis for three-drug combination studies.Studies on peptidyl nucleoside antibiotics: synthesis and antifungal evaluation of pyranosyl nucleoside analogs of nikkomycin.Large-Scale Evaluation of In Vitro Amphotericin B, Triazole, and Echinocandin Activity against Coccidioides Species from U.S. Institutions.Pharmacological agents in development for invasive aspergillosis.Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies.Fungal echinocandin resistance.Modeling the combination of amphotericin B, micafungin, and nikkomycin Z against Aspergillus fumigatus in vitro using a novel response surface paradigm.Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatusEffects of Echinocandins in Combination with Nikkomycin Z against Invasive Candida albicans Bloodstream Isolates and the fks Mutants2,3-Butanedione monoxime increases sensitivity to Nikkomycin Z in the budding yeast Saccharomyces cerevisiae.New agents for the treatment of systemic fungal infections--current status.Recent Insights into the Paradoxical Effect of Echinocandins.
P2860
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P2860
Drug interaction studies of a glucan synthase inhibitor (LY 303366) and a chitin synthase inhibitor (Nikkomycin Z) for inhibition and killing of fungal pathogens
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
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name
Drug interaction studies of a ...... nd killing of fungal pathogens
@ast
Drug interaction studies of a ...... nd killing of fungal pathogens
@en
Drug interaction studies of a ...... nd killing of fungal pathogens
@nl
type
label
Drug interaction studies of a ...... nd killing of fungal pathogens
@ast
Drug interaction studies of a ...... nd killing of fungal pathogens
@en
Drug interaction studies of a ...... nd killing of fungal pathogens
@nl
prefLabel
Drug interaction studies of a ...... nd killing of fungal pathogens
@ast
Drug interaction studies of a ...... nd killing of fungal pathogens
@en
Drug interaction studies of a ...... nd killing of fungal pathogens
@nl
P2860
P1476
Drug interaction studies of a ...... nd killing of fungal pathogens
@en
P2093
D A Stevens
P2860
P304
P356
10.1128/AAC.44.9.2547-2548.2000
P407
P577
2000-09-01T00:00:00Z