Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes - Wikidata - wikimedia - TriplyDB

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

http://www.wikidata.org/entity/Q28345343

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FTO: the first gene contributing to common forms of human obesity Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)Muscle atrophy in transgenic mice expressing a human TSC1 transgene The Aryl Hydrocarbon Receptor Relays Metabolic Signals to Promote Cellular Regeneration Post-transcriptional regulation in metabolic diseases Insulin-like growth factor-1 deficiency and metabolic syndrome Role of IGF-I signaling in muscle bone interactions Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth PPARs and the complex journey to obesity Insulin signaling regulates mitochondrial function in pancreatic beta-cells Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.Diabetic nephropathy in a nonobese mouse model of type 2 diabetes mellitus.Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression.Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis.Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.Intracerebroventricular leptin infusion improves glucose homeostasis in lean type 2 diabetic MKR mice via hepatic vagal and non-vagal mechanisms.Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus.Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes.The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes.Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes The proliferating role of insulin and insulin-like growth factors in cancer.Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.Two tales of antioxidant enzymes on β cells and diabetes.Anti-Inflammatory Action of Insulin via Induction of Gadd45-β Transcription by the mTOR Signaling Pathway.Mouse models of insulin resistance.Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy.Insulin resistance and pancreatic beta cell failure Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance.Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

http://www.wikidata.org/entity/Q28345343

description

2001 nî lūn-bûn

@nan

2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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Functional inactivation of the ...... muscle causes type 2 diabetes

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A L Castle

http://www.w3.org/2001/XMLSchema#string

A M Fernández

http://www.w3.org/2001/XMLSchema#string

C Hernandez-Sanchez

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D Le Roith

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G I Shulman

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J Dupont

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J Filmore

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J K Kim

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S Yakar

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P2860

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

Molecular and cellular aspects of the insulin-like growth factor I receptor

Troglitazone action is independent of adipose tissue

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.

Genetics of non-insulin-dependent (type-II) diabetes mellitus.

Insulin/IGF-1 hybrid receptors: implications for the dominant-negative phenotype in syndromes of insulin resistance.

Insulin/IGF-I receptor hybrids: a mechanism for increasing receptor diversity.

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality

Normal growth and development in the absence of hepatic insulin-like growth factor I

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1926-34

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478290

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10.1101/GAD.908001

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15

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15

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2001-08-01T00:00:00Z

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11857152

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11485987

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type-2 diabetes

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312754

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