Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides
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The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemicInduction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophagesInfection of monocytes by human immunodeficiency virus type 1 blocked by inhibitors of CD4-gp120 binding, even in the presence of enhancing antibodies2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriPotent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptaseSynergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitroCyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitroReplication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynuclDipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophagesActivities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophagesMacrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humansIdentification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidinePreclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitroCystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cellsEffects of 2',3'-dideoxyinosine on Toxoplasma gondii cysts in miceEffects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosidesThe NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytesPhosphorylation of nucleoside analog antiretrovirals: a review for clinicians.In vitro and in vivo evidence that the antiviral activity of 2',3'-dideoxycytidine is target cell dependent in a feline retrovirus animal model.Differential inhibition of 2'-deoxycytidine salvage as a possible mechanism for potentiation of the anti-human immunodeficiency virus activity of 2',3'-dideoxycytidine by dipyridamole.Differential antiviral activities and intracellular metabolism of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine in human cells.GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineageStructure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.Expression of interleukin 2 receptors by monocytes from patients with acquired immunodeficiency syndrome and induction of monocyte interleukin 2 receptors by human immunodeficiency virus in vitro.Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complex.Inhibition of dual/mixed tropic HIV-1 isolates by CCR5-inhibitors in primary lymphocytes and macrophages.Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcriptionAlpha interferon (2b) in combination with zidovudine for the treatment of presymptomatic feline leukemia virus-induced immunodeficiency syndrome.Antiretroviral therapy: reverse transcriptase inhibition.Selection of HIV resistance associated with antiretroviral therapy initiated due to pregnancy and suspended postpartum.WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.Proliferating cellular nuclear antigen expression as a marker of perivascular macrophages in simian immunodeficiency virus encephalitis.Comparison of the effects of 3'-azidothymidine with those of neutralizing antibodies on simian immunodeficiency virus infection in macrophages.Effect of 3'-azido-3'-deoxythymidine on human immunodeficiency virus type 1 replication in human fetal brain macrophages.Replication in vitro and in vivo of an equine infectious anemia virus mutant deficient in dUTPase activity.Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNAAntiviral therapy: current concepts and practicesT-cell-induced expression of human immunodeficiency virus in macrophagesUse of recombinant retroviruses to characterize the activity of antiretroviral compounds.
P2860
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P2860
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides
description
1988 nî lūn-bûn
@nan
1988 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@ast
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@en
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@nl
type
label
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@ast
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@en
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@nl
prefLabel
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@ast
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@en
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@nl
P2093
P2860
P356
P1476
Inhibition of human immunodefi ...... lated 2',3'-dideoxynucleosides
@en
P2093
D A Cooney
N R Hartman
R Yarchoan
T L Gerrard
Y A Wilson
P2860
P304
P356
10.1084/JEM.168.3.1111
P407
P577
1988-09-01T00:00:00Z