The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist
about
Molecular cloning and characterization of the human prostanoid DP receptorThe human prostanoid DP receptor stimulates mucin secretion in LS174T cellsMolecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl terminiIn vitro characterization of prostanoid FP-, DP-, IP- and TP-receptors on the non-pregnant human myometriumCharacterization of the prostanoid receptor types involved in mediating calcitonin gene-related peptide release from cultured rat trigeminal neuronesExpression of functional prostaglandin D (DP) receptors in human corpus cavernosum smooth muscleThromboxane A2 and related prostaglandins in airwaysUpdate on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugsThe role of prostanoid TP- and DP-receptors in the bronchoconstrictor effect of inhaled PGD2 in anaesthetized guinea-pigs: effect of the DP-antagonist BW A868CGlycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathwayReplacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compoundsPharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligandFPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptorsRegulation of endothelial nitric oxide synthase by PGD(2) in the developing choroidLigand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cellsCharacterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonistThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsAL-3138 antagonizes FP prostanoid receptor-mediated inositol phosphates generation: comparison with some purported FP antagonists.Prostanoid receptor antagonists: development strategies and therapeutic applicationsProstaglandin D2 DP1 receptor is beneficial in ischemic stroke and in acute exicitotoxicity in young and old miceLaropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation.Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.Inverse agonist and pharmacochaperone properties of MK-0524 on the prostanoid DP1 receptorA novel antagonist of prostaglandin D2 blocks the locomotion of eosinophils and basophils.Prostaglandin DP receptors positively coupled to adenylyl cyclase in embryonic bovine tracheal (EBTr) cells: pharmacological characterization using agonists and antagonists.Prostanoid receptors involved in the relaxation of human bronchial preparations.Prostanoid receptors involved in the relaxation of human pulmonary vesselsEffects of some isoprostanes on the human umbilical artery in vitro.Piglet saphenous vein contains multiple relaxatory prostanoid receptors: evidence for EP4, EP2, DP and IP receptor subtypes.Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.Classification of platelet and vascular prostaglandin D2 (DP) receptors: estimation of affinities and relative efficacies for a series of novel bicyclic ligands. With an appendix on goodness-of-fit analyses.In vitro characterization of prostanoid receptors on human myometrium at term pregnancyIdentification of a prostanoid FP receptor population producing endothelium-dependent vasorelaxation in the rabbit jugular vein.Modulation of noradrenaline release from the sympathetic nerves of the human saphenous vein and pulmonary artery by presynaptic EP3- and DP-receptors.Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene.Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs.The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responsesInhibition of prostaglandin D synthase suppresses muscular necrosis.The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.Prostaglandin D₂ and T(H)2 inflammation in the pathogenesis of bronchial asthma.
P2860
Q24323210-435CAEEB-98D9-4657-B0F9-67E5E71C98CBQ24674203-59570743-D054-4AF2-ACF7-E95D55F70216Q24679354-F467DA6F-FE26-4A1F-9A2C-967D82A6E0C2Q24680324-2CB613C5-D611-4029-805C-2C564052E223Q28191541-712A5600-60B7-489C-87A6-1F5271BDFCB5Q28218573-4A7EA02F-B42D-4C2B-84A7-A60277792845Q28240444-66C1A151-BDA2-4F34-975C-B247C0ABFA07Q28299410-8304C3D6-815C-4635-A93C-7A8A73C0CD41Q28329577-26500534-4E5A-43D7-A427-17352D5C1220Q28344289-839057DB-8836-434B-9100-5C29CA96A0ABQ28344638-92AD1FBE-02F7-4EF2-AFA7-0C56D7E77023Q28344925-CB6E20B0-FE28-462C-A3AA-3BC160B2723EQ28368421-8985C355-D679-4DC5-A30E-74B174FCDB88Q28369083-C87B68A4-64AF-4A6E-94C7-866C40E0EDDCQ28379138-930C773D-DE9E-4AF8-91EB-A29BCF5308B9Q28379508-D59EACF5-3E67-487B-918E-547903CF0BE9Q30486707-A8FA165B-211A-4084-818C-45C205321C4CQ31986643-D9812269-6213-4248-B976-3CB4CB4E3F7CQ33485483-F7AD7926-ADBE-48AF-A500-AA7C7B75A212Q34080404-455589F7-BDA1-41C2-A64F-B708B986EAC3Q34368772-082D527D-66B3-47E5-85D8-D511427F9573Q34597967-E4B263FF-916C-4987-93A9-B2FB3AE3AD7FQ34770179-41D57715-0B50-450F-802B-20B092212E9AQ34846451-52FA08B9-B419-4970-A7B7-7710E4CE6ABEQ35028755-2478C693-CDAE-4A03-B7AD-E148F5B36C52Q35041066-D9F68C4D-0DE3-48D4-8110-C1713CC02EA7Q35041074-69AB3A2C-4920-4FAE-B5B3-924E5CA7D5F9Q35041898-9C2BCDA4-BDE6-4614-80AD-C4D5562749A6Q35048608-DAF60872-2025-4EE1-8DF4-42005A04FE9FQ35578642-FEEC0A57-54B5-4B68-B86B-579E5A6C189FQ35870836-75E50AFF-4429-4B6C-91AA-88E7C25B065EQ35871450-8886EA23-B145-4354-BB2F-352FC067CB55Q35873157-BB25D21E-709D-4986-A04A-6CA295189F4EQ35874391-AE76296D-09F9-42F6-8A5B-F96170CCE301Q35900876-8E6B7681-ED03-475C-B83C-BA8B555932E0Q36856987-2CFE39D8-BA7B-404D-AD1E-9F92FA39ED15Q36983712-D0576ED1-CE1F-45B7-A09A-F8DAA1724AECQ37164193-93294AEB-50A8-415D-A987-71C5B16E1A1BQ37269228-8E3538DD-4ABB-41EC-BBBE-B84381EE6189Q37857703-D4C03668-08EA-45E4-9DB2-D1F625DB0BBF
P2860
The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
The classification of prostagl ...... potent competitive antagonist
@ast
The classification of prostagl ...... potent competitive antagonist
@en
The classification of prostagl ...... potent competitive antagonist
@nl
type
label
The classification of prostagl ...... potent competitive antagonist
@ast
The classification of prostagl ...... potent competitive antagonist
@en
The classification of prostagl ...... potent competitive antagonist
@nl
prefLabel
The classification of prostagl ...... potent competitive antagonist
@ast
The classification of prostagl ...... potent competitive antagonist
@en
The classification of prostagl ...... potent competitive antagonist
@nl
P2093
P2860
P1476
The classification of prostagl ...... potent competitive antagonist
@en
P2093
P2860
P304
P356
10.1111/J.1476-5381.1989.TB11816.X
P407
P577
1989-02-01T00:00:00Z