Analysis of crystal structures of aspartic proteinases: on the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes
about
Enzymic and structural characterization of nepenthesin, a unique member of a novel subfamily of aspartic proteinasesComputational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β -SecretaseCrystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid Protein ProductionStatistical Coupling Analysis of Aspartic Proteinases Based on Crystal Structures of the Trichoderma reesei Enzyme and Its Complex with Pepstatin ACrystal Structures of the Histo-Aspartic Protease (HAP) from Plasmodium falciparumStructural Insights into the Activation and Inhibition of Histo-Aspartic Protease from Plasmodium falciparumFlexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulationsStructure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801Crystal structure of a putative aspartic proteinase domain of theMycobacterium tuberculosiscell surface antigen PE_PGRS16Conformational Dynamics and Binding Free Energies of Inhibitors of BACE-1: From the Perspective of Protonation EquilibriaExploring the binding of BACE-1 inhibitors using comparative binding energy analysis (COMBINE).Structural studies of vacuolar plasmepsinsNovel method for probing the specificity binding profile of ligands: applications to HIV protease.N-Glycosylation Improves the Pepsin Resistance of Histidine Acid Phosphatase Phytases by Enhancing Their Stability at Acidic pHs and Reducing Pepsin's Accessibility to Its Cleavage SitesThe role of tyrosine 71 in modulating the flap conformations of BACE1.Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors.Aspartic proteinases from Mucor spp. in cheese manufacturing.Microbial aspartic proteases: current and potential applications in industry.Molecular dynamics studies on both bound and unbound renin protease.Assigning the protonation states of the key aspartates in β-Secretase using QM/MM X-ray structure refinementOn the orientation of the catalytic dyad in aspartic proteases.Is histoaspartic protease a serine protease with a pepsin-like fold?Pepsinogen-like activation intermediate of plasmepsin II revealed by molecular dynamics analysis.Database for three dimensional structures of pepsin-like enzymes using the internal coordinate system.Fragment-based virtual screening approach and molecular dynamics simulation studies for identification of BACE1 inhibitor leads.Mechanisms of peptide hydrolysis by aspartyl and metalloproteases.Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases.The catalytic mechanism of mouse renin studied with QM/MM calculations
P2860
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P2860
Analysis of crystal structures of aspartic proteinases: on the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@ast
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@en
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@nl
type
label
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@ast
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@en
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@nl
prefLabel
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@ast
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@en
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@nl
P2860
P3181
P1433
P1476
Analysis of crystal structures ...... ic site of pepsin-like enzymes
@en
P2093
N S Andreeva
P2860
P304
P3181
P356
10.1110/PS.25801
10.1110/PS.PS.25801
P407
P577
2001-12-01T00:00:00Z