The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
about
Population pharmacokinetics of mycophenolic acid in children and young people undergoing blood or marrow and solid organ transplantationRenal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite.In vitro-in vivo correlations for drugs eliminated by glucuronidation: investigations with the model substrate zidovudine.S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.A comparison of the effect of ciclosporin and sirolimus on the pharmokinetics of mycophenolate in renal transplant patients.Characterization of in vitro glucuronidation clearance of a range of drugs in human kidney microsomes: comparison with liver and intestinal glucuronidation and impact of albumin.Simultaneous quantification of mycophenolic acid and its glucuronide metabolites in human plasma by an UPLC-MS/MS assay.Pharmacokinetic principles of immunosuppressive drugs.Novel mechanisms of nonsteroidal anti-inflammatory drug-induced renal toxicity.Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability.Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics.Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearanceA perspective on efflux transport proteins in the liverAldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.Human clearance prediction: shifting the paradigm.The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic acid in solid organ transplantation and autoimmune diseasePharmacokinetic evaluation of mycophenolate mofetil for pemphigus.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.Gene expression study of phase I and II metabolizing enzymes in RPTEC/TERT1 cell line: application in in vitro nephrotoxicity prediction.Clinical Pharmacokinetics of Mycophenolic Acid in Hematopoietic Stem Cell Transplantation Recipients.Effect of long-term coadministration of compound glycyrrhizin tablets on the pharmacokinetics of mycophenolic acid in rats.Mycophenolate pharmacokinetics and association with response to acute graft-versus-host disease treatment from the Blood and Marrow Transplant Clinical Trials NetworkExtensive intestinal glucuronidation of raloxifene in vivo in pigs and impact for oral drug delivery.Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver.Comparative metabolism of mycophenolic acid by glucuronic acid and glucose conjugation in human, dog, and cat liver microsomes.Questionnaire-based evaluation of gastrointestinal disorders in de novo renal-transplant patients receiving either mycophenolate mofetil or enteric-coated mycophenolate sodium.Prediction of Free from Total Mycophenolic Acid Concentrations in Stable Renal Transplant Patients: A Population-Based Approach.Highly variable mycophenolate mofetil bioavailability following nonmyeloablative hematopoietic cell transplantation.Population pharmacokinetics of mycophenolic acid in lung transplant recipients with and without cystic fibrosis.Effects of poloxamer 407-induced hyperlipidemia on hepatic multidrug resistance protein 2 (Mrp2/Abcc2) and the pharmacokinetics of mycophenolic acid in rats.Pharmacokinetic Variability of Mycophenolic Acid in Pediatric and Adult Patients With Hematopoietic Stem Cell Transplantation.
P2860
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P2860
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@ast
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@en
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@nl
type
label
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@ast
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@en
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@nl
prefLabel
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@ast
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@en
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@nl
P2860
P1476
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
@en
P2093
J O Miners
K Bowalgaha
P2860
P356
10.1046/J.0306-5251.2001.01487.X
P407
P577
2001-11-01T00:00:00Z