New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs
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Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerabilityStructure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitorsPatterns of resistance and cross-resistance to human immunodeficiency virus type 1 reverse transcriptase inhibitors in patients treated with the nonnucleoside reverse transcriptase inhibitor lovirideSRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virusNon-nucleoside reverse transcriptase inhibitors: the NNRTI boom.In search of a selective antiviral chemotherapy.Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression.The discovery of antiviral agents: ten different compounds, ten different stories.Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs.The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study.Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): retroviruses and hepadnaviruses.Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors.Imidazo[1,5-b]pyridazine-d4T conjugates: synthesis and anti-human immunodeficiency virus evaluation.Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.A check on rational drug design: molecular simulation of the allosteric inhibition of HIV-1 reverse transcriptase.The combined anti-HIV-1 activities of emtricitabine and tenofovir plus the integrase inhibitor elvitegravir or raltegravir show high levels of synergy in vitro.What can be Expected from Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in the Treatment of Human Immunodeficiency Virus Type 1 (HIV-1) Infections?Computational modeling of tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepinone derivatives: an atomistic drug design approach using Kier-Hall electrotopological state (E-state) indices.Conformation depends on 4D-QSAR analysis using EC-GA method: pharmacophore identification and bioactivity prediction of TIBOs as non-nucleoside reverse transcriptase inhibitors.Long-read direct infrared sequencing of crude PCR products for prediction of resistance to HIV-1 reverse transcriptase and protease inhibitors.
P2860
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P2860
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@ast
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@en
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@nl
type
label
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@ast
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@en
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@nl
prefLabel
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@ast
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@en
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@nl
P2093
P2860
P356
P1476
New tetrahydroimidazo[4,5,1-jk ...... ',3'-dideoxynucleoside analogs
@en
P2093
H J Breslin
J Desmyter
M A Janssen
R Woestenborghs
P2860
P304
P356
10.1128/AAC.38.12.2863
P407
P577
1994-12-01T00:00:00Z