In vitro activity of aplidine, a new marine-derived anti-cancer compound, on freshly explanted clonogenic human tumour cells and haematopoietic precursor cells
about
Isolation and characterization of marine Brevibacillus sp. S-1 collected from South China Sea and a novel antitumor peptide produced by the strain.Marine-derived anticancer agents in clinical trials.Antitumor peptides from marine organismsMulticenter phase II study of plitidepsin in patients with relapsed/refractory non-Hodgkin's lymphoma.Synthetic studies of tamandarin B side chain analogues.Natural products as probes of cell biology: 20 years of didemnin research.Plitidepsin has a safe cardiac profile: a comprehensive analysis.Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs PathwaysEffect of Aplidin in acute lymphoblastic leukaemia cells.Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers.Preparation and Antitumor Activity of CS5931, A Novel Polypeptide from Sea Squirt Ciona SavignyiCXCR4-independent rescue of the myeloproliferative defect of the Gata1low myelofibrosis mouse model by Aplidin.Phase II study of biweekly plitidepsin as second-line therapy for advanced or metastatic transitional cell carcinoma of the urothelium.Plitidepsin: design, development, and potential place in therapy.Cell cycle phase perturbations and apoptosis in tumour cells induced by aplidine.Antiangiogenic activity of aplidine, a new agent of marine originAn Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs.Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas.In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug.Aplidin reduces growth of anaplastic thyroid cancer xenografts and the expression of several angiogenic genes.Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.Population pharmacokinetics meta-analysis of plitidepsin (Aplidin) in cancer subjects.Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK.In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development.Structure elucidation of aplidine metabolites formed in vitro by human liver microsomes using triple quadrupole mass spectrometry.Therapeutic Properties and Biological Benefits of Marine-Derived Anticancer Peptides.
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P2860
In vitro activity of aplidine, a new marine-derived anti-cancer compound, on freshly explanted clonogenic human tumour cells and haematopoietic precursor cells
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
In vitro activity of aplidine, ...... haematopoietic precursor cells
@ast
In vitro activity of aplidine, ...... haematopoietic precursor cells
@en
In vitro activity of aplidine, ...... haematopoietic precursor cells
@nl
type
label
In vitro activity of aplidine, ...... haematopoietic precursor cells
@ast
In vitro activity of aplidine, ...... haematopoietic precursor cells
@en
In vitro activity of aplidine, ...... haematopoietic precursor cells
@nl
prefLabel
In vitro activity of aplidine, ...... haematopoietic precursor cells
@ast
In vitro activity of aplidine, ...... haematopoietic precursor cells
@en
In vitro activity of aplidine, ...... haematopoietic precursor cells
@nl
P2093
P2860
P3181
P356
P1476
In vitro activity of aplidine, ...... haematopoietic precursor cells
@en
P2093
A R Hanauske
G T Faircloth
H Depenbrock
I Manzanares
P2860
P2888
P304
P3181
P356
10.1038/BJC.1998.570
P407
P577
1998-09-01T00:00:00Z
P5875
P6179
1049915064