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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

http://www.wikidata.org/entity/Q28369649

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Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis A new look at an old virus: patterns of mutation accumulation in the human H1N1 influenza virus since 1918 RNA virus error catastrophe: direct molecular test by using ribavirin Viral mutation rates Implications of genetic heterogeneity in cancer Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)Adaptation and immunity Do mutator mutations fuel tumorigenesis?Current perspectives on HIV-1 antiretroviral drug resistance The APOBEC3 family of retroelement restriction factors Viral quasispecies evolution Efficient Virus Extinction by Combinations of a Mutagen and Antiviral Inhibitors Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity Mutagenesis versus Inhibition in the Efficiency of Extinction of Foot-and-Mouth Disease Virus Ribavirin Reveals a Lethal Threshold of Allowable Mutation Frequency for Hantaan Virus A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape Protein tolerance to random amino acid change Retroviral restriction by APOBEC proteins Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations?Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461 Stochastic simulations suggest that HIV-1 survives close to its error threshold Lethal mutagenesis of bacteria T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro In search of new inhibitors of HIV-1 replication: synthesis and study of 1-(2'-Deoxy-beta-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide as a selective viral mutagenic agent.Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection.Mutator mutations enhance tumorigenic efficiency across fitness landscapes.Deciphering Evolutionary Mechanisms Between Mutualistic and Pathogenic Symbioses Human cancers express mutator phenotypes: origin, consequences and targeting.Variable mutation rates as an adaptive strategy in replicator populations.Evolution of biological information.Quasispecies theory and the behavior of RNA viruses.Optimization of DNA polymerase mutation rates during bacterial evolution.Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.Genomic mutation rates that neutralize adaptive evolution and natural selection Impacts of mutation effects and population size on mutation rate in asexual populations: a simulation study.Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.The relationship between the error catastrophe, survival of the flattest, and natural selection.The mutator phenotype in cancer: molecular mechanisms and targeting strategies Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine

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P2860

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

http://www.wikidata.org/entity/Q28369649

description

1999 nî lūn-bûn

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1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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1999 թվականի փետրվարին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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type

label

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

@ast

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

@en

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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prefLabel

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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P2093

F Kazazi

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J I Mullins

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J M Essigmann

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J Zhang

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K D Rose

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L A Loeb

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P2860

Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases

Purification of a mammalian homologue of Escherichia coli endonuclease III: identification of a bovine pyrimidine hydrate-thymine glycol DNAse/AP lyase by irreversible cross linking to a thymine glycol-containing oligoxynucleotide

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

RNA virus mutations and fitness for survival

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.

Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy.

Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations.

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10.1073/PNAS.96.4.1492

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9990051

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